The Rho family of GTPases is a family of small (~21 kDa) signaling G protein (more specific, a GTPase), and is a subfamily of the Ras superfamily. The members of the Rho GTPase family have been shown to regulate many aspects of intracellular actin dynamics, and are found in all ...
Small GTPases of the Rho Family and Cell Transformation. In: Jeanteur, P. (eds) Cytoskeleton and Small G Proteins. Progress in Molecular and Subcellular Biology, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58591-3_8 Download citation .RIS .ENW .BIB DOIhttps...
4. Ueyama T. Rho-family small GTPases: from highly polarized sensory neurons to cancer cells. Cells. 2019;8(2):92. 5. Grimsley-Myers CM, Sipe CW, Géléoc GS, et al. The small GTPase Rac1 regulates auditory hair cell morphogenesis. J Neurosci. 2009;29(50):15859-15869. 6. Antto...
Rho Family Small GTPases 来自 Springer 喜欢 0 阅读量: 105 作者: SB Heidelberg 摘要: The RHO genes code for a family of related proteins that can bind to and hydrolyze GTP. These proteins are similar to the Ras oncogenes and include RhoA, Rac1 and Cdc42. In the GTP‐bound state,...
过去的研究表明,细胞内的钙离子和Rho 家族的鸟苷三磷酸酶(Rho family of small GTPases,Rho GTPases)均可以介导轴突导向的信号通路,但两者之间的相互关系尚不清楚。 Ca～(2+)-dependent Regulation of Rho GTPases Trigg...
Rho family small GTPases are the key regulators of cytoskeletal organization and dynamics1,2and have been a subject of an extensive research effort in the biomedical community. Advanced molecular biosensors3,4,5and optogenetic tools6,7,8revealed a complex, coordinated spatiotemporal dynamics of Rho...
Cooperative activation of PI3K by Ras and Rho family small GTPases. Mol Cell 2012; 47: 281–290. CAS PubMed PubMed Central Google Scholar Kumar R, Gururaj AE, Barnes CJ . p21-activated kinases in cancer. Nat Rev Cancer 2006; 6: 459–471. CAS PubMed Google Scholar Chow HY, Jubb...
different signalingprotein domainswhich allow them to respond to a wide variety of signals and thus allow divergent signals to converge on a common small GTPase (Figure 4). In contrast, only a handful of GEFs have been identified for Rab family proteins, the largest family of sm...
Rho Family of GTPases分析和总结分析和总结.docx,Rho Family of GTPases Multimedia Contents The Dynamic Cytoskeleton Actin-based extensions motility Filopodia Lamellipodia Stress fibers Filopodia specific information is found HERE Rac Lamelliopodia/lamellum
Rho Family GTPases and Cancer TheRho family of GTPasesis a family of small signalingG proteinsthat have an approximate size of 21KDa[12]. The members of theRho GTPasefamily have been demonstrated to play critical roles in the biology of intra-cellular actin in most eukaryotes[13]. The th...