Knockdown of both ABCA1 and ABCG1 in macrophage reduced cholesterol efflux ex vivo and RCT in vivo to a greater extent than loss of function of either transporter alone (5). Consistent with this, transplantation of ABCA1/ABCG1 double knockout bone marrow into atherosclerosis-prone mice ...
Y. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8, 191–197 (2007). Article CAS PubMed Google Scholar Gangaplara, A. et al. Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor ...
We first knocked out glycerolphosphate dehydrogenaseGPD2in an alcohol dehydrogenases knock-out strain (鈻砤dh1-5) to increase the NADH availability for the pathway, which significantly increased the production of butyric acid (78mg/L) and hexanoic acid (2mg/L) when the pathway was expressed ...
The mouse with the Inadl insertion was produced in the process of obtaining knock-in (KI) mice with a point mutation in the CCHC zinc finger domain of Peg10 ORF1 by CRISPR/Cas co-injection with DNA oligos. The DNA oligos have 53 bp and 80 bp homologous regions and a T to G ...
Packaging and delivery Selling Units: Single item Single package size: 25.00X15.00X5.00 cm Single gross weight: 1.000 kg Show more Lead time Know your supplier Shenzhen Yuzens Technologies Co. Ltd. 10 yrsLocated in CN Order with confidence ...
ofOf与andAnd反向遗传分子 系统标签: ofsumolecularreversegeneticcharacterization遗传 MolecularandreversegeneticcharacterizationofNUCLEOSOMEASSEMBLYPROTEIN1(NAP1)genesunravelstheirfunctionintranscriptionandnucleotideexcisionrepairinArabidopsisthalianaZiqiangLiu1,2,YanZhu1,JuanGao1,2,FangYu1,2,†,AiwuDong1,*andWen-...
dsRNA targeting theMpC002gene, its partial silencing significantly reduced aphid reproduction rate, but not survival rate28. This was in contrast to the findings in wheat aphid (Schizaphis graminum) where a complete knock-down of theSgC002gene could cause high mortality of aphids45. This ...
Effect of Huxin Formula (护心方) on reverse cholesterol transport in ApoE-gene knockout mice 来自 Springer 喜欢 0 阅读量: 80 作者:Wei Jiang 江巍,Song Li 李松,Wei Mao 毛炜,Guang Yang 杨广,Xin-mei Li 李新梅,Guang-juan Zheng 郑广娟,Huan-lin Wu 吴焕林,Xin-min Ruan 阮新民,Ke-ji Chen ...
Preferably, at least 80, 85, 90, 95% reduction in activity is attained, and in the most preferred embodiment, the activity is eliminated (100%, aka a “knock-out” or “null” mutants). Proteins can be inactivated with inhibitors, by mutation, or by suppression of expression or ...
For example, suppose your $13,000 RCN investment includes an 80% knock-in (or barrier) level, and the underlying stock's initial price is $65. If during the term, the stock never closes at $52 or less, and the final price of the stock is higher than the knock-in price of $52, ...