To facilitate the genetic study of sleep, we documented that rest behavior in Drosophila melanogaster is a sleep-like state. The animals choose a preferred location, become immobile for periods of up to 157 min at a particular time in the circadian day, and are relatively unresponsive to ...
C. et al. Rest in Drosophila is a sleep-like state. Neuron 25, 129–138 (2000). 7. Ho, K. S. & Sehgal, A. Drosophila melanogaster: an insect model for fundamental studies of sleep. Methods Enzymol. 393, 772–793 (2005). 8. Koh, K., Evans, J. M., Hendricks, J. C. & ...
Rest in Drosophila Is a Sleep-like State To facilitate the genetic study of sleep, we documented that rest behavior in Drosophila melanogaster is a sleep-like state. The animals choose a preferred... JC Hendricks,SM Finn,KA Panckeri,... - 《Neuron》 被引量: 1193发表: 2000年 Adrenergic ...
networks (a.k.a. resting-state networks; or RSNs). Importantly, typical time-varying analyses (e.g., using sliding window-based approaches) have been prone to be affected by sampling variability and physiological artifacts in the fMRI data43,44. With that said, however, work using simultaneou...
activity. We suggest that periods of reduced synaptic input ('off periods' or 'down states') are necessary for such maintenance. This in turn requires a state of globally synchronized neuronal activity, reduced sensory input and behavioural immobility — the well-known manifestations of sleep. ...
Extended periods of rest in Drosophila melanogaster resemble mammalian sleep states in that they are characterized by heightened arousal thresholds and specific alterations in gene expression [1, 2]. Defined as inactivity periods spanning 5 or more min, amounts of this sleep-like state are, as in...