doi:10.1002/art.23437ObjectiveTo assess the clinical response to interleukin-1 (IL-1) blockade and in vitro IL-1β and IL-18 secretion in patients with systemic-onset juvenile idiopathic arthritis (JIA).EBSCO_AspArthritis & Rheumatism
The tw o form s o f interleukin-1, IL -la and IL -1[3 respectively, and tumour necrosis factor (TNF) are polypeptides sharing different biological activities which are often associated with host defence mechanisms. Because o f the well- recognized benefits o f breast feeding for newborns, ...
including interleukin-1 beta (IL-1 beta), interleukin-5 (IL-5), interleukin-6 (IL-6) interleukin-8 (IL-8), and tumor necrosis factor-alpha (TNF-alpha), in the sinonasal mucosa of patients with chronic rhinosinusitis, and evaluated the response of these cytokines to oral corticosteroids. ...
Polymorphism in intron 2 of the interleukin-1 receptor antagonist gene, local midtrimester cytokine response to vaginal flora, and subsequent preterm birth This study investigated the association between polymorphism in intron 2 of the interleukin-1 receptor antagonist gene, midtrimester vaginal microflora...
Based on previous reports39,40, genes related to pattern recognition receptors, antimicrobial peptides, complement molecules, lectin family members, cytokines in innate immunity, interleukin-1 family members and receptors, tumor necrosis factor, chemokines, and the major histocompatibility complex were ...
A spontaneous of BALB/c was transduced with the interleukin (IL)-2, , and interferon ()-gamma genes. The ability of clones releasing , or to form after s.c. challenge was compared to the TS/A parental cells (TS/A-pc) and to cells transduced with the resistance gene alone. Cytokine-...
Lactobacillus crispatus mediates anti-inflammatory cytokine interleukin-10 induc- tion in response to Chlamydia trachomatis infection in vitro. Int J Med ... Losacco,Antonio,Fiorentino,... - 《International Journal of Medical Microbiology Ijmm》 被引量: 19发表: 2015年 ...
Pro-inflammatory cytokines, such as interleukin-1 (IL-1) and tumour necrosis factor-alpha (TNF-alpha), are believed to play a role in the biological proces... J Andreas,D Zhang,K Afshar,... - 《Eur J Orthod》 被引量: 185发表: 2005年 Human histologic tissue response after long-term ...
Here, we show that the ‘interleukin 1 (IL-1)–interleukin 1 receptor antagonist (IL-1ra)’ axis regulates vaccine-mediated systemic inflammation in a host-specific manner. In human immune cells, RNA vaccines induce production of IL-1 cytokines, predominantly IL-1β, which is dependent on ...
In this study we used a keratinocyte cell line to identify the presence of substance P (SP) and calcitonin gene-related peptide (CGRP) receptors on keratinocytes and examined the effects of SP and CGRP stimulation on keratinocyte neuropeptide signaling, cell proliferation, and interleukin-1 beta (...