It is important to overcome resistance to change for two reasons. The first is that all creative ideas are by definition new and unexpected departures from the usual and the accepted. Resisting change therefore means opposing creativity and the progress it brings about. The second reason is that ...
The term “resistance to change” is commonly used in discussions about Lean. It simply means that people are set in their ways, and often don’t want to modify their routines.Surprisingly, this change resistance doesn’t just occur when people who like their jobs are asked to make a ...
Group antimicrobial administration is used to control disease in livestock, but we have little insight into how this impacts antimicrobial resistance (AMR) gene dynamics. Here, a longitudinal study was carried out during a single production cycle on a commercial pig unit with high historic and curre...
Co-evolution between plants and their natural enemies is generally believed to have generated much of the Earth's biological diversity. A process analogous to co-evolution occurs in agricultural systems, in which natural enemies adapt to crop resistance introduced by breeding or genetic engineering. ...
CLSI criteria did not produce a general change in resistance rates. Findings suggest the need to revise certain empirical criteria, such as aminoglycoside synergy for Enterococcus and for community-origin S. aureus. Keywords: significant bacteriuria; gram-positive bacteria; antibiotic resistances; urinary...
This combination of high fungicide efficacy and large pathogen population size means that even rare mutations altering sensitivity to the fungicide will be selected, and survive and propagate, provided there is no major fitness cost associated with the change. The vulnerability of single-site ...
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Tension and Resistance to Change in Organizational Climate: Managerial Implications for a Fast Paced World Climate is the atmosphere of the organization, a "relatively enduring quality of the internal environment of an organization, which is experienced by its members and influences their behavior." Th...
are inconsistent with the prevalent assumption of resistance achieved through a single (epi)mutational change, which converts tolerance to resistance, and instead support a gradual improvement of cell fitness under therapy. Next, we decided to characterize the mechanistic underpinning of the evolution ...
The term ‘extensive drug resistance’ should be defined as resistance to all but one or two classes of antimicrobial agents [2]. Previous studies have shown that two major mechanisms are involved in drug resistance, including a change in intrinsic chromosomally encoded resistance-related genes and...