he adds, because for many people, work is their most challenging activity. "Retirement is good for people who've had routine jobs—they may find something more stimulating. But it's disadvantageous for people in high-level jobs, who are less likely to find something...
Deconstruction and/as Resistance: Challenging the Ontological Foreclosure of Straussianism and Beyond„end of philosophy‟ - the problematic turn that signifies, among otherdevelopments, the Heideggerian critique of metaphysics and its many offspring -appears to pose something of a hurdle for ...
e.g. within about 1,500 bp on average in maize (Zea maysL.)26, a typical genome-wide AM may need tens of millions of markers to be accurately genotyped with numerous individuals, which is still challenging and
changes in gustatory receptors in a resistant population (glucose-aversive) to behavioral resistance23. Characterizing behavioral resistance in arthropods is a challenging task because it involves providing empirical evidence of heritable traits that are “evolved behaviors to reduce an arthropod’s exposure...
Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) is the most frequently mutated oncogene, occurring in a variety of tumor types. Targeting KRAS mutations with drugs is challenging because KRAS is considered undruggable due to the lack of classic drug bi
Given the many challenges to data collection and reporting caused by the COVID-19 pandemic,32, 33 as well as our collaborators' process of data collation and cleaning, we were unable to collect more contemporary data; we assumed no change in prevalence of resistance for 2019. First, we ...
were regarded as genes with an absolute log2 fold change > 0·25 andpadj < 0·05. violinplot functions were employed to visualize gene expression. volcano plots for the visualization of degs between nr and r were generated using the r package enhancedvolcano. enrichment analysis of ...
2) transcripts with a log2 (fold-change) value ≥ 1 were considered to be up-regulated; 3) transcripts with a log2 (fold-change) value ≤ -1 were considered to be down-regulated and 4) transcripts with a log2 (fold-change) value between 1 and -1 was considered as not regulated. ...
Conservation practices during the first decade of the millennium predominantly focused on resisting changes and maintaining historical or current conditions, but ever-increasing impacts from climate change have highlighted the need for transformative act
Anti-angiogenic therapies for cancer such as VEGF neutralizing antibody bevacizumab have limited durability. While mechanisms of resistance remain undefined, it is likely that acquired resistance to anti-angiogenic therapy will involve alterations of the