Despite such resistance to change, however, many new ideas do manage to take hold. We might think that when they do, those who had fought so hard for them would remember the resistance they had to overcome in others.Ironically, they often forget very quickly. In fact, they sometimes displa...
The author's expression of a wish for a situation to change can be interpreted as a request: the people referred to in the standpoint are requested in an indirect way to change their behaviour, or to undertake the action the author argues to be desirable. The example can therefore be ...
(B) Growth rate of resistant T47D cells compared to parental cells. (C) Real-time qPCR analyzing the fold change in mRNA expression between parental and resistant T47D cells (resistant to 100 nM palbociclib). Data are reported as the means ± SEMs of 3 independent experiments. ∗p < ...
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Crops expressing genes from Bacillus thuringiensis (Bt crops) are among the most successful technologies developed for the control of pests but the evolution of resistance to them remains a challenge. Insect resistant cotton and maize expressing the Bt V
A term rooted in Freudian psychoanalysis that refers to resistance by a psychotherapist that corresponds to the patient's resistance to closeness and change of life patterns. Examples include coming late to sessions, avoiding certain subjects, and fascination with the patient. Three types are counter...
A scientific-thinking change agent (a.k.a “a leader”) is going to step back and assess. Why did I get the reaction I did? What triggered it? What are the values of this constituency that are being challenged? Most pushback comes from a perceived threat to something that is regarded...
Transcriptome analysis following COS-5.44 treatment was performed and 1220 genes (~589 up- and ~631 down-regulated) showed significant differential expression relative to the wild type under the same growth conditions (P-value < 0.05 and log2 fold change ≥ 1 or ≤ − 1, Addit...
To become resistant, the virus would have to change many parts of the protein surface (i.e., it presents a high genetic barrier). In contrast, therapy with a monoclonal antibody (e.g., palivizumab for respiratory syncytial virus [RSV]) which targets a single epitope, would be more ...
The racial structures that restrict and shape Black social life change with time and place. Black people’s identities change with time and place because their sense of who they are similar to, and who they are different from, changes. The variety of historical ways of understanding blackness,...