The fight against cystic fibrosis (CF) has taken a major step forward, with pioneering research by University of Adelaide scientists showing that cells causing the debilitating genetic disorder could be successfully replaced with healthy ones. The research published in the journalStem Cell Research and...
Stanford U. research: Viruses supply new therapy for cystic fibrosisSusanna Fryer
A pilot study of aerosolized amiloride for the treatment of lung disease in cystic fibrosis. Excessive active absorption of sodium is a unique abnormality of the airway epithelium in patients with cystic fibrosis. This defect is associated with thi... MR Knowles,NL Church,WE Waltner,... - 《...
Cystic fibrosis (CF) is a genetic disease affecting multiple organs, in which, primarily the lungs and digestive system, become obstructed by mucus, causing difficulties in breathing and digesting food. Researchers have now found that people suffering from CF have limited ability to uptake and use ...
Cystic fibrosis is a genetic disorder driven by CFTR mutations that affects the exocrine glands. Manifesting with excessively viscous mucus production, patients typically experience obstruction of passageways (e.g., pancreatic and bile ducts, intestines, and bronchi). Lung disease is responsible for th...
1960, contains what seem to be stenographic transcriptions of the papers and discussions of a conference on Cystic Fibrosis held in Washington D.C., January 7-9, 1959, under the sponsorship of the National Institutes of Health in association with the National Cystic Fibrosis Research Foundation. ...
Background Chronic daily therapies (CDTs) are the foundation of clinical care for people with cystic fibrosis (CF), but these therapies impose considerable burden. In the era of elexacaftor/tezacaftor/ivacaftor (ETI) therapy, it is not clear if CDT discontinuation would lead to a greater decrea...
摘要: We summarized limb muscle abnormalities experienced by people with cystic fibrosis (CF). The focus of this overview was to describe the causes and consequences of limb muscle abnormalities in CF and how limb muscles respond to therapy (e.g. drugs or rehabilitation)....
A recent study led by Gergely Lukacs, a professor at McGill University's Faculty of Medicine, Department of Physiology, and published in the January issue of Cell, has shown that restoring normal function to the mutant gene product responsible for cystic
The research, conducted by CF-EpiNet—a Cystic Fibrosis Trust Strategic Research Centre (SRC) of which the University of Liverpool is a member—has shown that having CF results in lower average birth weight, revealing the need for further research into how CF affects the development of babies ...