First, the parental RNA serves as template for the synthesis of complementary RNA, then the minus strand serves as template for the synthesis of new viral RNA chains with the same polarity as the parental RNA (plus-strand RNA). This newly formed + RNA has three potential fates: a) it ...
关键词: BACTERIOLYSIS CARBON ISOTOPES CENTRIFUGATION COLIPHAGES ESCHERICHIA COLI EXPERIMENTAL LAB STUDY GENETIC CODE LIGASES METABOLISM NUCLEOTIDYLTRANSFERASES PHOSPHORUS ISOTOPES PRECIPITATION PROTEIN METABOLISM RADIOMETRY RIBONUCLEASE RIBOSOMES RNA, VIRAL VIRAL PROTEINS 被引量: 135 ...
B Perales,J Ortín - 《Journal of Virology》 被引量: 162发表: 1997年 The influenza A virus PB2 polymerase subunit is required for the replication of viral RNA. The transcription and replication of influenza virus RNA (vRNA) were reconstituted in vivo. The experimental approach involved the ...
MicroRNAs (miRNAs) are single﹕tranded nonヽoding RNA molecules. In addition to participating in various biological processes of eukaryotes, such as cell proliferation, development, differentiation, metabolism, tumorigenesis, and apoptosis, miRNAs also play an important role in the regulation of virus...
网络病毒的复制;病毒增殖;病毒的增殖
All genomes are replicated in a temporal order, though the determinants of such timing are poorly characterized. Here, the authors show that the unusual chromosome size-dependent DNA replication timing in Leishmania is influenced by RNA-DNA hybrids that are recognised by the endonuclease RNase H1....
The synthesis of viral RNA in φ6-infected cells was studied by polyacrylamide gel electrophoresis and density gradient centrifugation of total RNA labeled with [ 3H]uridine either in short pulses or cumulatively. Each of the three parental double-stranded RNA segments (M = 4.8, 2.9, and 2.2 ...
Influenza virus RNA polymerase is composed of three subunits, PB1, PB2 and PA, which is involved in both transcription and replication of viral genome RNA,... M Ejima,K Haraguchi,T Yamamoto,... - International Symposium on Micro-nanomechatronics & Human Science 被引量: 0发表: 2006年 Gene...
of this effector of innate immunity was mapped within its uniquecis-actingelements. This highly virus- and IFN-responsive chIFIT5 protein interacted with negative sense viral RNA structures that carried a triphosphate group on its 5′ terminus (ppp-RNA). This interaction reduced the replication of...
NoV contains a bipartite positive strand RNA genome: RNA1 encodes the viral RNA replicase, while RNA2 encodes the capsid protein. The role of RNA secondary structure in the genome replication of other RNA viruses has been well established. For NoV, sequences at the 3' end of RNA2 are ...