Clear cell renal cell carcinoma (ccRCC) displays molecular and histologic heterogeneity. Previously described subsets of this disease, ccA and ccB, were defined based on multigene expression profiles, but it is unclear whether these subgroupings reflect the full spectrum of disease or how these ...
Renal cell carcinoma is the most common primary malignancy of the kidney. This tumor accounts for 2% of all cancer diagnoses in humans [1]. Among the RCC histologic subtypes, the vast majority are classified as clear cell renal cell carcinoma (CCRCC) [2]. Although renal tumors are usually ...
So here's a nice example of a large renal cell carcinoma. You can see that this mass is huge. It's heterogeneous, it has areas of central necrosis and it apparently is involving the right renal vein and the IVC. All features that are very important to convey to the surgeon. Now even...
Renal cell carcinoma of clear-cell type (ccRCC) is an enigmatic tumor type, characterized by frequent inactivation of the VHL gene (infrequently mutated in other tumor types), responsiveness to angiogenesis inhibitors, and resistance to both chemotherapy and conventional radiation therapy. ccRCC tumors...
Clear cell renal cell carcinoma (ccRCC) is a complex disease with remarkable immune and metabolic heterogeneity. Here we perform genomic, transcriptomic, proteomic, metabolomic and spatial transcriptomic and metabolomic analyses on 100 patients with ccRCC from the Tongji Hospital RCC (TJ-RCC) cohort. ...
Results of a Multicenter Phase II Study of Atezolizumab and Bevacizumab for Patients With Metastatic Renal Cell Carcinoma With Variant Histology and/or Sarcomatoid Features. J Clin Oncol 2020;38:63-70. Tannir NM, Signoretti S, Choueiri TK, et al. Efficacy and Safety of Nivolumab Plus Ipilimumab...
网络释义 1. 肾透明细胞癌 肾透明细胞癌(Clear Cell Renal Cell Carcinoma)是肾细胞癌中最常见的病理类型,约占70%～80%,因此筛选和鉴定肾透明细胞癌 … cdmd.cnki.com.cn|基于8个网页 2. 透明细胞肾细胞癌 透明细胞肾细胞癌(clear cell renal cell carcinoma), 多房性囊性透明细胞肾细胞癌(multilocular cl...
E. et al. Systemic therapy for non-clear cell renal cell carcinomas: a systematic review and meta-analysis. Eur. Urol. 67, 740–749 (2015). Google Scholar Kroeger, N. et al. Metastatic non-clear cell renal cell carcinoma treated with targeted therapy agents: characterization of survival ...
Objective To analyze the relationship between contrast-enhanced ultrasound (CEUS) features of clear cell renal cell carcinoma (CCRCC) to TNM stage and Fuhrman grades. Methods CEUS appearance of 50 CCRCCs confirmed pathologically were retrospectively analyzed. For each lesion, the homogeneity of enhanceme...
Integrated molecular analysis of clear-cell renal cell carcinoma. Nat Genet 2013;45:860-7.Sato Y, Yoshizato T, Shiraishi Y, Maekawa S, Okuno Y, Kamura T, et al. Integrated molecular analysis of clear-cell renal cell carcinoma. Nature Genetics. 2013; 45(8):860-U191. doi: 10.1038/ng....