Iconography : Clear Cell Renal Cell CarcinomaDavid J GrignonMingxin Che
Renal cell carcinoma (RCC), one of the top ten most prevalent malignancies worldwide, predominantly manifests as clear cell RCC (ccRCC)1,2,3. Metabolic deregulation is a key characteristic of ccRCC4. To date, most clinical metabolomic studies have focused solely on metabolomic profiling5,6, le...
Clear cell-papillary renal cell carcinoma (CC-Pap RCC) is a recently described renal tumor initially reported in the setting of end-stage renal disease (ESRD). It has unique morphologic and immunohistochemical features that differentiate it from the more common clear cell RCC and papillary RCC. ...
·100 g).There is significant statistical difference between two groups(P 0.01).Most CTU tumors are uniform density and rich blood supply.Conclusions MSCT perfusion imaging can quantitatively assess hemodynamics variation of renal clear cell carcinoma,combined with CTU imaging can reflect the form and...
Renal cell carcinoma is the most common primary malignancy of the kidney. This tumor accounts for 2% of all cancer diagnoses in humans [1]. Among the RCC histologic subtypes, the vast majority are classified as clear cell renal cell carcinoma (CCRCC) [2]. Although renal tumors are usually ...
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The histologic diagnosis may be challenging as the presence of small blue cells on biopsy may be mistaken for a lymphoma involving the prostate or a small cell carcinoma of the prostate, diagnostic possibilities that are statistically ... S Logani,RA Cabrera,MB Amin - 《Pathology Case Reviews》...
Kidney Renal Clear Cell Carcinoma (KIRC) accounts for 75% of all renal cancers. Previous study had conflict evidences regarding NR1B2 role in cancer, and its expression and biological role in KIRC remained unclear. Our aims were to characterize the role
BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is characterized by high constitutive vascular endothelial growth factor A (VEGF-A) production that induces a specific vascular phenotype. We previously reported that this phenotype may allow shedding of multicellular tumor fragments into the circulation...
Intratumoral heterogeneity (ITH) is a hallmark of clear cell renal cell carcinoma (ccRCC) that reflects the trajectory of evolution and influences clinical prognosis. Here, we seek to elucidate how ITH and tumor evolution during immune checkpoint inhibit