Mutations in the NF-κB signaling pathway: implications for human disease. Oncogene 2006; 25: 6831–6843. 11 Grumont RJ, Gerondakis S. The subunit composition of NF-κB complexes changes during B-cell development. Cell Growth Differ 1994; 5: 1321–1331. 12 Liou HC, Sha WC, Scott ML, ...
nucleus. Is expressed in axial skeleton; eye; heart; and ureter. Used to study atopic dermatitis. Human ortholog(s) of this gene implicated in breast cancer and immunodeficiency 53. Orthologous to human RELB (RELB proto-oncogene, NF-kB subunit). [provided by Alliance of Genome Resources, ...
Alternative NF-κB signalling is stimulated by TRAF3 autophagy.aA549 cells were transfected with the indicated siRNA for 72 h and immunoblotted as shown (p100 and p52 indicate parental and processed NFκB2, respectively).b,cA549 WT, ΔATG5and/or rescue cell clones were immunoblotted as shown...
Anomaly Detection and Artificial Intelligence Identified the Pathogenic Role of Apoptosis and RELB Proto-Oncogene, NF-kB Subunit in Diffuse Large B-Cell LymphomaARTIFICIAL intelligenceB cell lymphomaPROTO-oncogenesMACHINE learningPROGNOSISBackground: Diffuse large B-cell lymphoma (DLBCL) is one of the ...
Genomic organization and expression of the rearranged REL proto-oncogene in the human B-cell lymphoma cell line RC-K8. Genes Chromosomes Cancer 2002, 34, 129-135. [CrossRef] [PubMed]Kalaitzidis D, Gilmore TD. Genomic organization and expression of the rearranged REL proto-oncogene in the ...
The c-rel protooncogene product c-Rel but not NF- kappa B binds to the intronic region of the human interferon-gamma gene at a site related to an interferon-stimulable response element. Proc Natl Acad Sci U S A. 1992;89(5):1740-1744....
Anomaly Detection and Artificial Intelligence Identified the Pathogenic Role of Apoptosis and RELB Proto-Oncogene, NF-kB Subunit in Diffuse Large B-Cell LymphomaBackground: Diffuse large B-cell lymphoma (DLBCL) is one of the most frequent lymphomas. DLBCL is phenotypically, genetically, and ...
NF-kBRelThe human c-rel proto-oncogene (REL) encodes a subunit of the nuclear factor-kappaB (NF-κB) transcription factor. In this report, we have identified an identical point mutation in two human B-cell lymphomas (follicular (FL) and mediastinal) that changes serine (Ser)525 (TCA) to...
Anomaly Detection and Artificial Intelligence Identified the Pathogenic Role of Apoptosis and RELB Proto-Oncogene, NF-kB Subunit in Diffuse Large B-Cell LymphomaBackground: Diffuse large B-cell lymphoma (DLBCL) is one of the most frequent lymphomas. DLBCL is phenotypically, genetically, and ...