Garrod's proposition, attributing a defective enzyme to a defective gene, was the first ever to suggest a direct link betweengenesand proteins. Given that thenucleuswas known to house thegenetic material, which had already been identified asdeoxyribonucleic acid(DNA), several investigators subsequently...
252 PUBLICATION Relationship between genes expression, proteins induction, polymorphisms and radiotherapy complications in Saudi cancer patientsdoi:10.1016/S1359-6349(05)80550-6ELSEVIEREuropean Journal of Cancer Supplements
A large complex of proteins, including RNA polymerase II and its associated general transcription factors, which is necessary for the transcription of protein-coding genes. TATA box Named after its conserved DNA sequence, the TATA box is a non-coding DNA sequence found in many eukaryotic core pro...
But the process that translates genes into proteins turned out to be much more involved than anticipated. Other elements—proteins, snippets of RNA, regions of the genome that act as binding sites, and chemical groups that attach to DNA—also regulate protein production, complicating the relationsh...
Discover the function of chromatin. See what chromatin looks like and where in a cell it is located. Explore chromatin’s function in many cell processes. Related to this Question What is the relationship between DNA and proteins? How are chromatin, chromosomes, and DNA related?
Objective To study the relationship between gene polymorphism of Surfactant Protein B(SPB)-18 and neonatal respiratory distress symdrome susceptibility.Methods Totally 100 neonates diagnosed with NRDS and 186 gestational age,gender and birth weight matched neonates were enrolled from May.2009 to Dec.2010...
Polymerase chain reaction was used to amplify across variable restriction sites of the COLI A1 and COLI A2 genes that encode the alpha 1 and 2 subunits of type I collagen. The relationship between these polymorphisms and bone mineral density (BMD) was studied in 683 Chinese men and women. In...
Specifically, the relationship between obesity and deep periodontal pockets was independent of glucose tolerance status, suggesting a direct association between obesity and periodontitis [8]. Body mass index (BMI; calculated as weight in kilograms divided by the square of height in meters) was ...
Epigenetic clocks are mathematically derived age estimators that are based on combinations of methylation values that change with age at specific CpGs in the genome. These clocks are widely used to measure the age of tissues and cells1,2. The discrepancy
181Genes Involved in Platelet Activity and Thrombosis are Overexpressed in Human CD34+ Derived Megakaryocytes Driven to High Ploidy IntroductionMean platelet volume is increased in the setting of acute myocardial infarction (AMI) and is a poor prognostic marker despite antiplatelet use. The megakaryocyte...