The aim of the current study was to validate whether a key regulator of Gq signaling, regulator of G protein signaling 2 (RGS2), can inhibit Gα_q-mediated UM cell growth. We used two UM cell lines, 92.1 and Mel-202, which both contain the most common activating mutation Gα_q~Q...
Regulators of G protein signaling (RGS) bind to G subunits of G proteins and stimulate their GTPase activity, which 'switch off' G-protein-mediated signaling events. However, the role of RGS proteins in regulating endothelial permeability in response to G protein coupled receptor-agonists remains ...
(regulator of G-protein signalling 2) as being highly expressed in the Sca-1- 33A10Low/- population, which included myoepithelial/basal cells. RGS2 has previously been described as a regulator of angiotensin II receptor signalling. Gene expression analysis by quantitative real-time RT-PCR of ...
OPEN Citation: Cell Death and Disease (2017) 8, e2821; doi:10.1038/cddis.2016.216 Official journal of the Cell Death Differentiation Association www.nature.com/cddis Regulator of G protein signaling 2 is a key regulator of pancreatic β-cell mass and function H Dong1,2,7, Y Zhang1,2,7,...
上海玉博生物科技有限公司 主要致力于“Anti-RGS2((regulator of G-protein signaling 2) G蛋白信号转导调节因子2抗体 yb-0492R”的生产销售。多年的“Anti-RGS2((regulator of G-protein signaling 2) G蛋白信号转导调节因子2抗体 yb-0492R”生产与销售的经验,与各行业
Prostate cancer (PC) represents the second highest cancer-related mortality among men and the call for biomarkers for early discrimination between aggressive and indolent forms is essential. Downregulation of Regulator of G-protein signaling 2 (RGS2) has
该RGS2, Recombinant, Human, aa1-211, His-Tag (Regulator of G-protein Signaling 2)产品的产品序列,详细查看产品说明书。来源宿主 提供的RGS2, Recombinant, Human, aa1-211, His-Tag (Regulator of G-protein Signaling 2)来源为大肠杆菌中重组表达。溶解...
Drugs targeting individual G protein–coupled receptors are used as asthma therapies, but this strategy is limited because of G protein–coupled receptor signal redundancy. Regulator of G protein signaling 2 (RGS2), an intracellular selective inhibitor of multiple bronchoconstrictor receptors, may play...
Regulator of G-Protein signaling 2 Basic information More.. Product Name: Regulator of G-Protein signaling 2 Synonyms: Regulator of G-Protein signaling 2 CAS: MF: MW: 0 EINECS: Mol File: Mol File Information Error Report Your Email: ...
CAS号: 英文名: Regulator of G-Protein signaling 2 英文别名: Regulator of G-Protein signaling 2 中文名: 中文别名: CBNumber: CB04940896 分子式: 分子量: 0 MOL File: Mol file 化学性质 安全信息 用途 供应商 1 Regulator of G-Protein signaling 2化学性质 ...