Journal of Cellular BiochemistryRand E,Cedar H. Regulation of imprinting:A multi-tiered process[J].Journal of Cellular Biochemistry,2003,(02):400-407.doi:10.1002/jcb.10352.Rand E, Cedar H. 2003. Regulation of imprinting: A multi-tiered process. J Cell Biochem 88:400-407....
Circadian regulators are known to control the organism’s metabolism, including mitochondrial uncoupling;2,53 the relationship between circadian regulation, metabolism, and lifespan is highly complex. Here we showed that the male circadian mutant per01 is long-lived due to a mechanism independent of,...
many sets of dietary guidelines have already been reported to be capable of extending lifetime in at least one model organism and improving health conditions in humans. Considering the dissimilarity across populations
This followed from the realization by several groups (Kacser and Burns, 1973; Heinrich and Rapoport, 1974; Savageau, 1976) that analysis of multi-enzyme systems needed to go beyond the methods of analysing the kinetics of isolated enzymes.99 In particular, which enzyme, if any, controls the...
Orchestration of the immune response : Multilevel regulation of diverse regulatory processes 来自 Semantic Scholar 喜欢 0 阅读量: 26 作者:SL Swain,JC Cambier 摘要: Background Biologically relevant molecular markers can be used in evaluation of the physiological state of an organism in biotechnical ...
1B). Thus, the multiorgan, postnatal genetic program is highly conserved in mice and rats. Figure 1 Open in figure viewer A multiorgan postnatal genetic program common to mice and rats. A) Venn diagrams showing the number of genes significantly down-regulated and up-regulated with age by ...
Advancing tools to integrate multi-omics data, we develop functional inference of gene regulation (FigR), a framework to computationally pair scATAC-seq with scRNA-seq cells, connect distal cis-regulatory elements to genes, and infer gene-regulatory networks (GRNs) to identify candidate ...
Heart regeneration is a fascinating and complex biological process. Decades of intensive studies have revealed a sophisticated molecular network regulating cardiac regeneration in the zebrafish and neonatal mouse heart. Here, we review both the classical
constitutes a group of proteins where all the members studied to date are involved in ribosome-related functions2,3,4,5,6,7,8,9,10,11,12,13,14,15,16. They are widespread in bacteria and eukaryotes and in general, paralogues are present in the same organism, such asEscherichia coliwhich...
Cognitive function relies on a balanced interplay between excitatory and inhibitory neurons (INs), but the impact of estradiol on IN function is not fully understood. Here, we characterize the regulation of hippocampal INs by aromatase, the enzyme respon