For example, N-3 PUFA have been reported to decrease lipoprotein secretion from the gut and liver, as well as reduce apolipoprotein B-48 mRNA expression [19, 20]. This means that decreases in the TAG AUC may not stem from an increased rate of clearance by WAT exclusively, as the ...
Abstract: P432 REGULATION OF HIGH-DENSITY LIPOPROTEIN PARTICLE METABOLISM WITH PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR) BETA/DELTA AGONIST IN THE METABOLIC SYNDROMEPublication » Abstract: P432 REGULATION OF HIGH-DENSITY LIPOPROTEIN PARTICLE METABOLISM WITH PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (...
The immune-inflammatory response is associated with increased nitro-oxidative stress. The aim of this mechanistic review is to examine: (a) the role of redox-sensitive transcription factors and enzymes, ROS/RNS production, and the activity of cellular antioxidants in the activation and performance of...
Lipoproteins play a key role in regulating plasma and tissue levels of cholesterol. Apolipoprotein B (apoB)-containing lipoproteins, including chylomicrons, very-low density lipoprotein (VLDL) and low-density lipoprotein (LDL), serve as carriers of trigl
C. FoxO3 transcription factor and Sirt6 deacetylase regulate low density lipoprotein (LDL)-cholesterol homeostasis via control of the proprotein convertase subtilisin/kexin type 9 (Pcsk9) gene expression. J. Biol. Chem. 288, 29252–29259 (2013). Article CAS PubMed PubMed Central Google Scholar ...
This general region of steroidogenic cells is referred to as the microvillar compartment, and the specialized spaces created between adjacent microvilli are called microvillar channels. It is the microvillar channels where the various lipoproteins are trapped prior to the selective uptake of lipoprotein...
For downregulated DEGs, GO analysis of biological process such as diacyl- glycerol metabolic process, response to amino acid and low-density lipoprotein particle clearance may not relate to cancer (Fig. 6d). In addition, the biological process of GO analysis of upregulated DEGs between LOXL2vsCon...
Inflammation further decreases HDL levels by inducing the upregulation of sPLA2 which degrades phospholipid components of the lipoprotein particle [89]. Loss of LCAT activity [97, 98] reduces the cholesterol carrying capacity of HDL by preventing the formation of cholesterol esters. Finally, PON1 ...
Abstract: P432 REGULATION OF HIGH-DENSITY LIPOPROTEIN PARTICLE METABOLISM WITH PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR) BETA/DELTA AGONIST IN THE METABOLIC SYNDROMEdoi:10.1016/s1567-5688(09)70727-5E OoiG WattsD ChanD SprecherH Barrett
2012). The adhesion of Wnt protein to heparan sulfate proteoglycans (HSPGs) that are expressed on the cell surface enables Wnts to exist stably and migrate across the cell surface (Binari et al. 1997; Yan and Lin 2009). Extracellular proteins, such as Swim, lipoprotein particle (LPP), ...