11). However, the level of 3H and 14C clearance (as a percent of injected dose) was roughly equal in Gpihbp1−/− mice and, outside of BAT, also roughly equal in Angptl4−/−Gpihbp1−/− mice (Fig. 10). These data suggest that whole lipoprotein particle clearance occurs ...
Easier than LDL-C to combine with glycoprotein, deposit on arterial wall, and result in impaired clearance of plasma lipoprotein particles, sdLDL had been proved its crucial role in arteriosclerosis and cardiovascular disease27. With the highest sensitivity for predicting acute coronary events30, the ...
Important contribution of lipoprotein particle number to plasma triglyceride concentration in type 2 diabetes . Atherosclerosis 137 , 211 – 214 .Steiner G, Tkacˇ I, Uffelman KD, Lewis GF (1998) Impor- tant contribution of lipoprotein particle number to plasma triglyceride concentration in type 2...
S., 1980, Particle purification and characterization of the low density lipoprotein receptor from the bovine adrenal cortex, J. Biol. Chem. 255:11442–11447 PubMed CAS Google Scholar Shelburne, F., Hanks, J., Meyers, W., and Quarfordt, S., 1980, Effect of apoproteins on hepatic ...
BMI: body mass index; FPG: Fasting Plasma Glucose; HOMA-β: Homeostatic Model Assessment of Insulin beta-cell function; HOMA-IR: Homeostatic Model Assessment of Insulin Resistance; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; WHR: Waist/hip circumference...
It is proposed that heme-containing peroxidases (hPx) are major mediators of lipoprotein oxidization. Vascular peroxidase 1 (VPO1) is a recently-discovered hPx, which is expressed in cardiovascular system, lung, liver etc. and secreted into plasma. Its plasma concentration is three orders of ...
suggest that the size and relative amount of HDL lipid determine the HDL stability and the fraction of apo A-I that partitions into the aqueous phase where it is destined for interaction with ABCA1 transporters, thereby initiating reverse cholesterol transport or, alternatively, renal clearance. ...
Dependence of plasma alpha-tocopherol flux on very low-density triglyceride clearance in humans To evaluate the effect of dietary fat-induced alterations in triglyceride (TG) metabolism on plasma and very low-density lipoprotein (VLDL)-alpha-tocopherol, nine healthy males (mean +/- SEM, age: 36...
The plasma parameter log (TG/HDL-C) as an atherogenic index: correlation with lipoprotein particle size and esterification rate inapob-lipoprotein-depleted... The plasma parameter log (TG/HDL-C) as an atherogenic index: correlation with lipoprotein particle size and esterification rate inapob-...
In contrast to mammalian cells, bloodstream forms of Trypanosoma brucei show no activity for fatty acid and sterol synthesis and critically depend on plasma low density lipoprotein (LDL) particles for their rapid growth. We report here that these parasites acquire such lipids by receptor-mediated ...