Cell Adhesion Molecules组织白细胞细胞粘着分子Surgical wounds within previously irradiated tissues are subject to an increased incidence of postoperative complications including microvascular occlusion and impaired wound healing. The high radiation sensitivity of the vasculature has previously mainly been linked ...
- 《Journal of Cell Biology》 被引量: 324发表: 1995年 Glycosylation in the control of selectin counter-receptor structure and function Selectin counter-receptor activity on leukocyte and high endothelial venules is borne by specific glycoproteins whose ability to support adhesion requires ... JB ...
Leukocyte recruitment plays a major role in the immune response to infectious pathogens and during inflammatory and autoimmune disorders. The process of leukocyte extravasation from the blood into the inflamed tissue requires a complex cascade of adhesive events between the leukocytes and the endothelium ...
Lymphocyte function-associated antigen 1 (LFA-1) is a leukocyte cell surface glycoprotein that promotes intercellular adhesion in immunological and inflamm... SD Marlin,TA Springer - 《Cell》 被引量: 3823发表: 1987年 n−3 Polyunsaturated fatty acids inhibit the antigen-presenting function of human...
Intercellular Adhesion Molecule-1E-SelectinP-SelectinBackground. Severe acute pancreatitis (AP)2 is associated with exaggerated leukocyte adherence and activation. Endothelial cellular adhesion molecules (CAMs) can be induced by cytokines, but also directly by oxygen free radic...
- 《Journal of Leukocyte Biology》 被引量: 144发表: 1997年 PSA-NCAM in postnatally generated immature neurons of the olfactory bulb: a crucial role in regulating p75 expression and cell survival. In the mammalian brain, ongoing neurogenesis via the rostral migratory stream (RMS) maintains ...
A central feature of host defence is the ability of leukocytes to enter tissues in response to immune or inflammatory stimuli. The leukocyte adhesion molec... Spertini,G S,Kansas,... - 《Nature》 被引量: 666发表: 1991年 Regulation of Fibroblast Migration on Collagenous Matrix by a Cell Su...
Cell 112, 645–657 (2003). Using the Cre– loxP system with Cre expression under control of the lysozyme M promoter, the authors showed that HIF1α deficiency in macrophages causes metabolic defects as a consequence of inhibited glycolysis and results in an impaired inflammatory response. CAS ...
Herein we use LTβR-specific cell permeable peptides to selectively target separate arms of the NFκB pathway and reveal the molecular mechanism of leukocyte migration. The results show that constitutive and stimulated afferent LEC LTβR signaling preferentially engage the NIK pathway, resulting in ...
Interendothelial junctions and their role in the control of angiogenesis, vascular permeability and leukocyte transmigration. Endothelial cell-cell junctions play an important role in vascular hemostasis. The two junctional proteins VE-cadherin and JAM-1 are localized at adherens ... D Elisabetta,S ...