Liver-gut axis in the regulation of iron homeostasis. World J Gastroenterol. 2007;13:4737-4745.Darshan D. and Anderson G. J. (2007) Liver-gut axis in the regulation of iron homeostasis. World J.Darshan, D., & Anderson, G. J. (2007). Liver-gut axis in the regulation of iron ...
Regulation of iron homeostasis by microRNAs (Review) Iron homeostasis is maintained at the cellular and systemic levels to assure adequate iron supply while preventing iron overload. The identification of gen... M Castoldi,MU Muckenthaler - 《Cellular & Molecular Life Sciences Cmls》 被引量: 0...
In plants, iron homeostasis is tightly regulated to supply sufficient amounts of this metal for an optimal growth while preventing excess accumulation to avoid oxidative stress. To identify new regulators of iron homeostasis, a luciferase-based genetic screen using the Arabidopsis AtFer1 ferritin promo...
Arthritic rats develop a long-lasting anemia19 with the features of ACD. We used this animal model to study differences in the regulation of iron homeostasis between ACD, IDA, and ACD/IDA, the utility of serum hepcidin levels to discriminate between these different entities, and to study ...
The development of thermogenic adipocytes concurs with mitochondrial biogenesis, an iron-dependent pathway. Iron regulatory proteins (IRP) 1 and 2 are RNA-binding proteins that regulate intracellular iron homeostasis. IRPs bind to the iron-response element (IRE) of their target mRNAs, balancing iron...
Hepcidin, a peptide hormone made in the liver, is the principal regulator of systemic iron homeostasis. Hepcidin controls plasma iron concentration and tissue distribution of iron by inhibiting intestinal iron absorption, iron recycling by macrophages, and iron mobilization from hepatic stores. Hepcidin ...
EnvironmentalandExperimentalBotany114(2015)48–56ContentslistsavailableatScienceDirectEnvironmentalandExperimentalBotanyjournalhomepage:.elsevier.com/locate/envexpbotMolecularbasisandfitnessimplicationsoftheinterplaybetweenlightandtheregulationofironhomeostasisinphotosyntheticorganismsBerondaL.Montgomerya,b,∗,SookyungOha...
Regulators of iron homeostasis: new players in metabolism, cell death, and disease. Trends Biochem. Sci. 41, 274–286 (2016). Article CAS PubMed Google Scholar Gao, M. et al. Ferroptosis is an autophagic cell death process. Cell Res. 26, 1021–1032 (2016). Article CAS PubMed PubMed...
Hepcidin, a small cationic liver derived peptide, is a master regulator of body iron homeostasis. Cytokines and iron availability have so far been identified as regulators of hepcidin expression. Herein, we investigated the functional role of Kupffer cells for hepcidin expression because of their vici...
These findings demonstrate that the cardioprotective effects of caloric restriction result from the cellular regulation of iron homeostasis, thereby decreasing oxidative stress, inflammation, and cardiac remodeling. We suggest that decreasing iron-mediated oxidative stress and inflammation offers new therapeutic...