of nutrient transporter genes such as sglt, glut, and fabp is decreased while the expression of the eaat gene is increased when chickens are exposed to heat stress. the uptake of nutrients is affected by their respective tra...
This lesson will discuss the concept of gene regulation, how genes are regulated, as well as some mechanisms that enable it. It will also cover the...
including a stem containing 5 'splice sites of the 3' intronAnd (II) aptamersWhereThe aforementioned selectively spliced exonWhen spliced to target gene mRNAThe aforementioned selectively spliced exonIncluding the target gene and the stop codon of the inframeProvide a polynucleotide cassette.Diagram...
In the late phase of M1 macrophage polarization, increased histone lactylation induces homeostatic genes that are involved in wound healing, including Arg1. Collectively, our results suggest that an endogenous ‘lactate clock’ in bacterially challenged M1 macrophages turns on gene expression to promote...
Correlation analyses of gene expression in the somatic embryogenesis stages of tea. (A) Venn diagram of gene expression at different stages of occurrence. (B) Scatter plot of DEGs in different stages. (C) The DEGs cluster heat map between different stages. PS preliminary stage, IS intermediate...
FOXP3 physically interacts with both Siva isoforms.A. Diagram showing the Siva protein domain organization (SAH, spherical amphipathic helix; DDHR, death domain homology region; and Zn F, zinc finger) and a cartoon representation of Siva-1 and Siva-2, which were fused to the C-terminus of ...
These properties in turn shape the outcome of gene expression by modulating RNA processing, localization, translation, and eventual decay. m6A, the most common modification in mRNA, occupies an exocyclic amine that participates in Watson-Crick base pairing. Watson-Crick base pairing of m6A with U...
We identified the DNA-binding sites of each protein by using chromatin immunoprecipitation coupled to ultra-sequencing (ChIP-seq). Then, we determined growth phenotypes of as well as gene expression changes by transcriptomics in strains in which the candidate proteins had been overexpressed or mutated...
Of course, there are other techniques to identify a potential disease in the DNA/RNA structures. The loose of homochirality of DNA may indicate an age-related disease [6]. Data mining techniques may be employed to identify cancer in gene expression [7]. The role of miRNAs in the regulatio...
A deeper understanding of genetic regulation and functional mechanisms underlying genetic associations with complex traits and diseases is impeded by cellular heterogeneity and linkage disequilibrium. To address these limits, we introduce Huatuo, a framework to decode genetic variation of gene regulation at...