2002. Regulation of cell-substrate adhesion by the lipoxygenase and cyclooxygenase branches of arachidonic acid metabolism. Adv Exp Med Biol 507: 525 - 529.Roberts, L. A., H. L. Glenn, R. A. Whitfield & B. S. Jacobson: Regulation of cell-substrate adhesion by the lipoxygenase and ...
We have found that the cAMP-dependent protein kinase (PKA) is required for both mAb 12G10-induced cell-cell and cell-substrate adhesion of HT-1080 cells. Binding of mAb 12G10 to beta(1) integrins stimulates an increase in intracellular cAMP levels and PKA activity, and a concomitant shift ...
We also highlight recent in vitro approaches using individual embryonic stem cells and self-organizing multicellular models of human embryos, which have been instrumental in expanding our understanding of how mechanics tune cell fate and cellular rearrangements during human embryonic development. This is ...
Cell quiescence resulting from culture of normal human fibroblasts in low serum (0.5%) was associated with a subsequent gradual increase in the expression of the cell-surface glycoprotein VLA-1, and a corresponding decrease in the expression of extracellular matrix adhesion receptors VLA-2 and VLA-...
ArticleMechanical regulation of substrate adhesion and de-adhesion drives a cell-contractile wave during Drosophila tissue morphogenesisAuthor links open overlay panelClaudio Collinet 1, Anaïs Bailles 1 3, Benoit Dehapiot 1 4, Thomas Lecuit 1 2 5...
FZD7 knockdown induces phenotypic changes by rearrangement of actin cytoskeleton and strengthening of cell–cell adhesion. IF staining for β-catenin and F-actin in (a) CH1, (b) PA-1 and (c) OV-17R cell lines, respectively, after transfection with the negative control, FZD7-6 or FZD7-5...
Potential extracellular substrates, which serve as targets of a redox modification, are soluble pericellular proteins and ectodomains of transmembrane proteins. Redox changes in soluble proteins alter their conformation and function in biological processes such as cell signaling, adhesion, migration, ...
Differential regulation of CD4 + T cell adhesion to cerebral microvascular endothelium by the β-chemokines CCL2 and CCL3 . Int J Mol Sci... K Liu,K Dorovini-Zis - 《International Journal of Molecular Sciences》 被引量: 13发表: 2012年 Differential Regulation of CD4+ T Cell Adhesion to ...
Smooth muscle cells are able to adapt rapidly to chemical and mechanical signals impinging on the cell surface. It has been suggested that dynamic changes ... WT Gerthoffer,SJ Gunst - 《Journal of Applied Physiology》 被引量: 691发表: 2001年 Quantitative studies of endothelial cell adhesion. ...
These structures allow the transfer of signals from the external matrix to the cytoskeleton and facilitate cell adhesion, spreading, and migration. Focal contacts are composed of numerous proteins, including integrins, cadherins, focal adhesion kinase (FAK), and various other ECM and cytoskeletal ...