This article will focus on some of the major mechanisms that regulate cell migration at distinct points in the process: (1) the induction and guidance of migration, (2) cytoskeletal changes that underlie migration, and (3) the interaction of a migrating cell with its environment....
Integrin receptors play an important role during cell migration by mediating linkages and transmitting forces between the extracellular matrix and the actin cytoskeleton. The mechanisms by which these linkages are regulated and released during migration are not well understood. We show here that cell-per...
of some correlative congenital diseases as well.Cell migration dramatically occurs during the three germ layers formation at gastrula,generation of straight heart tube and delamination of neural crest after neural tube closure.In this review,we will discuss the current research progresses of the cell ...
Regulation of cell migration by amphoterin Amphoterin, a major form of HMG (high mobility group) 1 proteins, is highly expressed in immature and malignant cells. A role in cell motility is suggested... C Fages,R Nolo,HJ Huttunen,... - 《Journal of Cell Science》 被引量: 478发表: 20...
Migration of human glioma cells (hGCs) within the brain parenchyma makes glioblastoma one of the most aggressive and lethal tumors. Studies of the cellular and molecular mechanisms underlying hGC migration are hindered by the limitations of existing glio
0013 Effect of RNA interference mediated inhibition of VASP expression level on migration and invasion of human mammary epithelial tumor cells Profilin-1 (Pfn1 - a ubiquitously expressed actin-binding protein) levels are significantly downregulated in various invasive adenocarcinomas including bre... G ...
Induction of stable CCR7 homodimerization resulted in enhanced CCR7-dependent cell migration and CCL19 binding, whereas induction of CXCR4/CCR7 heterodimerization did not. In contrast, dissociation of CCR7 homodimerization by a novel CCR7-derived synthetic peptide attenuated CCR7-dependent cell migration, ...
作者: J Yong,X Luo,Key Laboratory of Industrial Microbiology,Ministry of Education College of Biotechnology,Tianjin University of Science and Technology Tianjin,China 展开 摘要: Recent studies have demonstrated that aquaporin (AQP) expression facilitates cell migration and promotes angiogenesis and ...
et al. Differential molecular and anatomical basis for B cell migration into the peritoneal cavity and omental milky spots. J. Immunol. 180, 2196–2203 (2008). Article CAS PubMed Google Scholar Baumgarth, N. B-1 cell heterogeneity and the regulation of natural and antigen-induced IgM ...
It has long been proposed that the cell cycle is regulated by physical forces at the cell–cell and cell–extracellular matrix (ECM) interfaces1–12. However, the evolution of these forces during the cycle has never been measured in a tissue, and whether