use of metoclopramide in single doses up to 20 mg prior to the provoking situation may be preferred rather than continuous treatment. Occasionally, patients (such as elderly patients) who are more sensitive to the therapeutic or adverse effects of metoclopramide will require only 5 mg per dose....
The preferred parenteral solution is Sodium Chloride Injection (normal saline), which when combined with REGLAN Injection (metoclopramide injection) , can be stored frozen for up to 4 weeks. REGLAN Injection (metoclopramide injection) is degraded when admixed and frozen with Dextrose-5% in Water. R...
A 77-week study was conducted in rats with oral doses of metoclopramide up to 40 mg/kg/day (about 5 times the maximum recommended human dose on surface area basis). Metoclopramide elevatesprolactinlevels and the elevation persists during chronic administration. Tissue culture experiments indicate ...