The inability to replace these AlO x complex ions by alkali metal ion exchange indicates their complex structure. These extraframework AlO x species localized inside the zeolite void volume of beta zeolites represent highly active sites in the stereoselective MPV reduction of ketone to cis-alcohol, ...
Alternatively, we propose that the reaction starts with the DHT process to form alcohol and NH2BH2, followed by alcoholysis of NH2BH2 to form the first B–O bond. This mechanism is in good agreement with the current experimental facts, and also explains why ketone reduction affords different ...
DOI: 10.1038/s41467-017-00226-y. (Open in a new window)PubMed (Open in a new window)Web of Science ®(Open in a new window)Google Scholar Kamitanaka, T.; Matsuda, T.; Harada, T. Mechanism for the Reduction of Ketones to the Corresponding Alcohols Using Supercritical 2-Propanol. ...
Artificial metalloenzymes derived from bovine β-lactoglobulin for the asymmetric transfer hydrogenation of an aryl ketone – synthesis, characterization and catalytic activity. Dalton Trans. 43, 5482–5489 (2014). Article CAS Google Scholar Merkler, D. J. & Schramm, V. L. Catalytic mechanism ...
[translate] aNoyori’s asymmetric reduction of ketone 141 using ruthenium catalyst 142 gave the (R)-propargylic alcohol in 98% ee. 酮141的Noyori的不对称的减少使用钌催化剂142在98% (ee)给了R - propargylic酒精。 [translate] 英语翻译 日语翻译 韩语翻译 德语翻译 法语翻译 俄语翻译 阿拉伯语翻译 ...
STEREOSELECTIVE REDUCTION PROCESS FOR THE PREPARATION OF PYRROLOTRIAZINE COMPOUNDS The invention relates to a process for the enzymatic, stereoselective reduction of ketone compounds to provide chiral alcohols, for example the compound of formula Ib RN Patel,LNH Chu,RM Johnson,... - US 被引量: 31...
In another work, ketone reduction using continuous flow process was also performed using S. cerevisiae immobilized on chrysotile fibers in a packed-bed-reactor (Scheme 11) (Wendhausen et al., 1998). 2.1.2 Reduction by other microorganisms The screening of new microorganisms is an important metho...
The reaction mechanism of Clemmensen reduction has not completely been clarified, but it is well known that the alcohol is not an intermediate. As summarized in Scheme 3,8,14 the reduction is thought to occur on the zinc metal surface, and involves protonation of the carbonyl function and a ...
The reverse reaction, where alcohols are oxidized to aldehydes and ketones, became known as the Oppenauer oxidation. As the MVP reaction is completely reversible, removal of the lower boiling ketone or addition of excess isopropyl alcohol is required to shift ...
Our engineered mutants exhibit significantly higher activity, up to 37-fold, and broader substrate specificity compared to the parent enzyme. The key to success is due to the well-tuned hydride attack distance/angle and, more importantly, to the synergistic proton-delivery triade of Tyr28-Tyr69-...