Ketones are readily reduced to secondary alcohols with sodium hydroxide in refluxing isopropanol.doi:10.1080/00397910903061043Zuidema, Daniel R.Wert, Katherine J.Williams, Sarah L.Chill, Samuel T.Holte, Kimberly L.Kokes, Nathanael K.Mebane, Robert C.Taylor & FrancisSynthetic Communications...
Secondary alcohols are oxidized to ketones with a much lower efficiency. Very high chemoselectivities are observed when primary alcohols are oxidized in the ... J Einhorn,C Einhorn,F Ratajczak,... - 《Cheminform》 被引量: 368发表: 1997年 Catalytically reactive (η4-tetracyclone)(CO)2(H)2Ru...
Combined gas-liquid chromatography-mass spectrometry of the secondary alcohols and ketones from broccoli ( Brassica oleracea) showed that the former consisted of a mixture of nonacosan-14-ol (43%) and nonacosan-15-ol (57%) whereas the latter contained predominantly nonacosan-15-one (92%). ...
Ketonesare one of the most important functional groups in organicchemistryand the AH of ketones is one the most direct and efficient methods for the construction of chiral secondary alcohols, which are key building blocks in many important pharmaceuticals (Fig. 1), pesticides, perfumes,natural produ...
(Chemical Equation Presented) Productive cells: In a simple, highly efficient process for the synthesis of optically active alcohols, ketones are reduced b... H Gröger,F Chamouleau,N Orologas,... - 《Angew Chem Int Ed Engl》 被引量: 307发表: 2006年 Asymmetric reductions of propargyl keto...
In a process for the reduction of ketones, the keto compounds are enantioselectively reduced to give secondary alcohols by means of microorganisms. Keto compounds of the formulaR.sup.3 NH- -CHR.sup.1 --CO--CH.sub.2 --COOR.sup.2in which R... Hans-Eckart Radunz,H Schwartz,M Heinrich ...
For example, the larger I69W showed a higher binding energy (−0.48 kJ/mol) compared to that of the wt parent (−1.13 kJ/mol), while the smaller I69V, I69A and I69G mutants resulted in significantly reduced binding energy. The latter can be attributed to the lower steric ...
In the previous reaction, the aldehyde group is converted into an acetal group, thus preventing reaction at this site when further reactions are run on the rest of the molecule. Notice in the previous reaction that the ketone carbonyl group has been reduced to an alcohol by reaction with LiAlH...
Primary alcohols (C/sub 1/ to C/sub 8/ tested) were not oxidized. The purified SADH and extracts of various yeasts and bacteria also catalyzed the reduction of methylketones to the corresponding secondary alcohols in the presence of reduced NAD/sup +/ as an electron donor. Both reactions ...
Convenient and inexpensive procedure for oxidation of secondary alcohols to ketones 来自 Semantic Scholar 喜欢 0 阅读量: 3 作者:RV Stevens,K Chapman,H Weller 摘要: ether became symnietrical in the presence of 5 equiv of 18-crown-6. Comparison of the chemical shift data for the anions of 1...