Weinreb amidePartial reductionAldehydeChloromagnesium dimethylaminoborohydride (ClMg+ [H3BNMe2], MgAB) is an analogue of the versatile lithium dialkylaminoborohydrides (LAB reagents), prepared by the reaction of dimethylamine-borane with methylmagnesium chloride. MgAB is a partial reducing agent for ...
Interactive 3D chemistry animations of reaction mechanisms and 3D models of chemical structures for students studying University courses and advanced school chemistry hosted by University of Liverpool
As the enzyme responsible for the reduction of Megazol within the parasite has not yet been identified, the nitroimidazole was assayed with T. cruzi lipoamide dehydrogenase and trypanothione reductase. Megazol did not inhibit the physiological reactions but proved to be a weak substrate of both ...
A number of similar ring contractions are known of dihydrobenz-azepinones to dihydroquinol-2-ones. The ester (814) with acid gives the quinolone (815) 〈55JA5932〉, while the amide (816) is converted by heat into compound (817) (a mixture of cis and trans isomers) 〈69HCA1929〉. ...
the average molar ratio of added formaldehyde to amide compound must be greater than 1. Quite commonly, the agents used are dimethylol compounds, such as, N,N'-dimethylolethylene urea, N,N'-dimethylolurea, N,N-dimethylolethyl carbamate, N,N'-dimethylol dihydroxyethylene urea, N,N'-dimethylol...
Interactive 3D chemistry animations of reaction mechanisms and 3D models of chemical structures for students studying University courses and advanced school chemistry hosted by University of Liverpool
Synthesis and structural characterisation of M(salen)-COFs We conducted two synthesis routes for M(salen)-COFs from the simple alicylaldehyde ligand, i.e. one-step and two-step syntheses (Fig.1). The one-step synthesis can construct M(salen)-COFs via four-component reactions and exhibits re...
Redox flow batteries (RFBs) are a promising stationary energy storage technology for leveling power supply from intermittent renewable energy sources with demand. A central objective for the development of practical, scalable RFBs is to ...
yield a stableamidebond. Due to the small size of azide, the reaction's bioorthogonality, and the mild reaction conditions involved, the Staudinger-Bertozzi ligation has been used extensively in several fields. For example, Raines and coworkers utilized a variant of the Staudinger-Bertozzi ...
In order to access enantiomerically enriched furofuranoid fragment127, cyclopropanation ofbutenolide124in the presence of Müller's catalyst (125)[47]followed bythermolysisof thecyclopropaneadduct126led to127. Sequential hydrogenation,lactonereduction, –OTBS protection and amide formation afforded the bicycli...