endosomeneuronal polarityprotein sortingsynaptic plasticityNeurons are highly polarized cells with axonal and somatodendritic membrane surfaces that spatially separate signal-sending from signal-receiving membrane domains. As found in many other cell types, different populations of endosomes are involved in the...
Retrograde membrane traffic is where proteins and glycolipids are transported back from the plasma membrane (PM) and endosomes to the Golgi and is essential for a wide range of cellular functions. In recent years, studies have begun to show that recycling endosomes (REs), a specific class of e...
The Recycling Endosome of Madin-Darby Canine Kidney Cells Is a Mildly Acidic Compartment Rich in Raft Components Plasma-MembraneEpithelial-CellsTransferrin ReceptorFusion InvitroWe present a biochemical and morphological characterization of recycling endosomes containing the ... R Gagescu,N Demaurex,RG Pa...
Retrograde membrane traffic is where proteins and glycolipids are transported back from the plasma membrane (PM) and endosomes to the Golgi and is essential for a wide range of cellular functions. In recent years, studies have begun to show that recycling endosomes (REs), a specific class of ...
Recycling endosomes maintain plasma membrane homeostasis and are important for cell polarity, migration, and cytokinesis. Yet, the molecular machineries that drive endocytic recycling remain largely unclear. The CORVET complex is a multi-subunit tether r
appendagesEndosome-proteins localize to centrosomes independent of membranes Rab11 and its modulators localize to mother centriole appendages Mother centriole appendages regulate membrane recycling through Rab11doi:10.1016/j.cub.2012.08.022Heidi HehnlyChun-Ting Chen...
J. Membrane transport: take your fusion partners. Curr. Biol. 9, R258–R260 (1999). Article CAS PubMed Google Scholar Woodman, P. G. Biogenesis of the sorting endosome: the role of Rab5. Traffic 1, 695–701 (2000). Article CAS PubMed Google Scholar Gruenberg, J., Griffiths, G....
Endocytosed cell surface membrane proteins rely on various recycling pathways for their return to the plasma membrane1. Although endosome-to-plasma membrane recycling is critical for many cellular processes2, much of the required machinery is unknown. We discovered that yeast also has a recycling ...
Retrograde transport is where proteins and lipids are transported back from the plasma membrane (PM) and endosomes to the Golgi, and crucial for a diverse range of cellular functions. Recycling endosomes (REs) serve as a sorting station for the retrograd
We introduced fluorescent markers of the Golgi (GRIP::mCherry), early endosome (RAB-5::mCherry) and RE (RAB-11::mCherry) into ccm-3( À / À ) (Fig. 3a,e–g). Ablation of ccm-3 did not affect early or late endosomes (RAB-7::mCherry), but caused a severe dispersal of ...