L., and Y. Yarden (Editors), 2015 Receptor Tyrosine Kinases: Structure, Functions and Role in Human. Humana Press Springer, New York.D. L. Wheeler and Y. Yarden, Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease, Springer, 2014....
Receptor tyrosine kinases (RTKs) are membrane proteins that control the flow of information through signal transduction pathways, impacting on different aspects of cell function. RTKs are characterized by a ligand-binding ectodomain, a single transmembrane -helix, a cytosolic region comprising ...
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Receptor tyrosine kinases are a subclass of cell-surface growth-factor receptors with an intrinsic, ligand-controlled tyrosine-kinase activity. They regulate diverse functions in normal cells and have a crucial role in oncogenesis. Twenty years ago, the first primary structure of a receptor tyrosine...
Receptor tyrosine kinases Receptor tyrosine kinases(RTKs) are a family ofcell surface receptorsfor growth factors, hormones,neurotrophic factors, and other extracellular signaling molecules. All RTKs share a similar structure composed of an extracellular ligand-binding domain, atransmembrane domain, and ...
受体酪氨酸激酶( receptor tyrosine kinases)为单次跨膜蛋白,包括6个亚族。配体与受体的结合导致受体二聚化,二聚体内彼此相互磷酸化胞内段酪氨酸残基
J. Schlessinger Cell signaling by receptor tyrosine kinases Cell, 103 (2000), pp. 211-225 View PDFView articleView in ScopusGoogle Scholar Schubert and Heinz, 2003 W.D. Schubert, D.W. Heinz Structural aspects of adhesion to and invasion of host cells by the human pathogen Listeria monocytoge...
Receptor tyrosine kinases (RTKs) play an important role in a variety of cellular processes including growth, motility, differentiation, and metabolism. As such, dysregulation of RTK signaling leads to an assortment of human diseases, most notably, cancer
Google Share on Facebook receptor (redirected fromReceptor tyrosine kinases) Thesaurus Medical Encyclopedia re·cep·tor (rĭ-sĕp′tər) n. 1.PhysiologyA specialized cell or group of nerve endings that responds to sensory stimuli. 2.BiochemistryA molecular structure or site on the surface or...