(2015). Recent developments in epigenetics of acute and chronic kidney diseases. Kidney Int 88, 250-261.Reddy MA, Natarajan R (2015) Recent developments in epigenetics of acute and chronic kidney diseases. Kidney Int 88:250–261 Central
Recently, there have been many research developments in the field of genomics, comprising mainly the ongoing transition from traditional 'monogenic genetics' towards comprehensive testing of the human genome by integrating massively parallel sequencing (MPS; or synonym 'next generation sequencing') approach...
In the following article, key developments and advances are summarized and current methods and tools reviewed. Keywords: epigenetics, DNA methylation, histone modifications, computational modeling, data analysis, advances, sequencing, databases 展开 ...
remarkable improvement in response to first-line therapy has boosted a surge of clinical trials focused on perioperative anti-PD-1/PD-L1 therapy in GI tract cancers [10,11,12,13,14,15,16,17,18,19,20,21,22,23]. Additionally, chimeric antigen receptor T-cell (CAR-T) therapy, exerts pot...
The advent of single-cell RNA sequencing (scRNA-seq) has provided insight into the tumour immune microenvironment (TIME). This review focuses on the application of scRNA-seq in investigation of the TIME. Over time, scRNA-seq methods have evolved, and com
Recent developments on the role of epigenetics in obesity and metabolic disease. The increased prevalence of obesity and related comorbidities is a major public health problem. While genetic factors undoubtedly play a role in determinin... J Susan,V Dijk,L Ross,... - 《Clinical Epigenetics》 ...
Epigenetics refers to the mitotically heritable modifications in gene expression which do not involve changes within the genetic code. Epigenetic mechanisms are rather complex, including a combination of molecular, chemical and environmental factors (constituting the epigenome) together with the genome, in...
- 《Epigenetics》 被引量: 27发表: 2014年 NEW TRENDS IN CIM: VIRTUAL MANUFACTURING SYSTEMS FOR NEXT GENERATION MANUFACTURING The paper provides a structured review on recent developments and new trends in CIM-related technologies and business strategies, and presents a new human-centered CIM ...
These developments suggest growing interest in and potential for YK-029A as a treatment option for patients with advanced NSCLC.184,185 Covalent EGFR inhibitors in terminated clinical trials With the emergence of new covalent EGFR inhibitors entering clinical trials, some clinical trials involving EGFR...
Data management – new developments Data resources and types While PubMed records over 50,000 papers on epigenetics to date, with more than a third of these appearing since 2013, data generation discussions have been dominated by the intra-generational rather than the inter-generational processes (...