Epigenetics: linking early development with adult diseaseHeijmans, Bas
The gene–environment interactions resulting from famine and the subsequent increased intergenerational risk of type 2 diabetes mellitus (T2DM) have contributed to the current epidemic of T2DM in China, which poses major social, health and economic chall
Epigenetics and the underpinnings of vulnerability Bulletin on Early Childhood Development 2015; 12(1):10 The inheritability of PTSD: Identifying the vulnerable Bulletin on Early Childhood Development 2015; 12(1):11 Prevention of mental illness: why not start at the beginning?
To this end, appropriate animal models are being developed in which early environmental factors can be manipulated in a controlled manner. Here we will review recent studies performed with the common aim of understanding the effects of the early environment in shaping brain development and discuss ...
The gene–environment interactions resulting from famine and the subsequent increased intergenerational risk of type 2 diabetes mellitus (T2DM) have contributed to the current epidemic of T2DM in China, which poses major social, health and economic challenges. The epidemic of T2DM could threaten nationa...
Comprehensive clinical studies show that adverse conditions in early life can severely impact the developing brain and increase vulnerability to mood disorders later in life. During early postnatal life the brain exhibits high plasticity which allows env
Epigenetics and Development of Food Allergy (FA) in Early Childhood This review aims to highlight the latest advance on epigenetics in the development of food allergy (FA) and to offer future perspectives. FA, a condition c... Xiumei,Hong,Xiaobin,... - 《Curr Allergy Asthma Rep》 被引量...
Obesity, diabetes, and cardiovascular and mental health disorders are increasingly recognized as connected with epigenetic changes of early origin. Epigenetics has qualified Mendelian theory in that randomization studies need not only assume a random distribution of alleles in the offspring, but also a ...
In this chapter, we will present that early embryonic development is very vulnerable to environmental influences. Therefore, from all phases of our life, embryogenesis is the period, where epigenetics has the largest impact. Epigenetics directs the programing of PGCs, induced pluripotency as well as...
Development: nature and nurture: Development – Genetics, Epigenetics and Environmental Regulation This document is an editorial published in the journal Frontiers in Genetics. It discusses the topic of fertilization and early development, specifically f... VEA Russo,DJ Cove,LG Edgar,... - 《Journal...