These studies have shown that the enhanced nucleophilicity of the platinum center to alkyl halides promotes smooth oxidative addition and that the charge rebalance accelerates the dissociation of the halide anion from the platinum(IV) intermediate, which is essential in the carbon–carbon bond-forming ...
Substituted pyridylphenylcarbinols are formed in the reaction of the dianions of isomeric pyridyl phenyl ketones with alkyl halides, aldehydes, and benzonitrile. The reaction of the dianion of 3-pyridyl phenyl ketone with benzophenone, in contrast to the analogous reaction of the dianion of 2-...
Lithium trialkylzincates were also reported to be useful as metalating reagents of aromatic halides or vinyl halides. The outer shell of the zinc atom in a lithium trialkylzincate is filled with16 electrons, and there is a room for an additional ligand to coordinate to form a favorable 18...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "...
A variety of pentafluorophenyltin compounds were prepared and their chemical properties were examined. These compounds effectively catalyzed Mukaiyama-aldol reaction of ketene silyl acetal in sharp contrast to the inertness of normal alkyltin halides like Bu2SnCl2. The increased Lewis acidity of the ...
However, reports of the M〩 reaction of internal olefins are rare and impractical due to low reactivity of internal olefin and problem of product diastereoselectivity. In this review, we summarise M〩 reactions of internal olefins with arylor alkyl halides.doi:10.1002/ajoc.201900741...
Tri--butylphosphine-catalyzed acylation of mixed -alkyl phenylzincs with aromatic acyl halides in THF is efficient in selective transfer of -alkyl groups to produce -alkyl aryl ketones in good yields. This route provides an atom economic organocatalyzed alternative to transition metal-catalyzed ...
2-Alkylmercapto-4-hydroxy-3,4,5,6-tetrahydro- and 2-alkylmercapto-3,6-dihydropyrimidines were synthesized by the reaction of substituted 4-hydroxyhexahydro- and 1,2,3,6-tetrahydropyrimidine-2-thiones with alkyl halides. It is shown that the nucleophilic center in the alkylation is the ...
The benzylic hydrogen atom in oxabicyclic tetrazoles such as (6 R,8 R)-(8-phenyl-5,6-dihydro-8 H-tetrazolo[5,1- c][1,4]oxazin-6-yl)-alkanols ( A, X=CH 2OH) is highly acidic, being alkylated in preference to a hydroxymethyl group with NaH and active alkyl halides. The ...
Tri- n-butylphosphine-catalyzed acylation of mixed n-alkyl phenylzincs with aromatic acyl halides in THF is efficient in selective transfer of n-alkyl groups to produce n-alkyl aryl ketones in good yields. This route provides an atom economic organocatalyzed alternative to transition metal-catalyzed...