Ohmiya,H.,Yorimitsu,H.,Oshima,K.Cobalt(diamine)-catalyzed cross-coupling reaction of alkyl halides with arylmagnesium reagents: Stereoselective constructions of arylated asymmetric carbons and application to total synthesis of AH13205.Journal of the American Chemical Society. 2006...
Intermolecular Heck reaction of common alkyl halides, a longstanding problem in palladium catalysis, is realized with a simple Pd/dppf catalyst. Both primary and secondary alkyl halides are suitable for coupling with aromatic olefins. Single electron transfer from (dppf)Pd0to alkyl halide initiated the...
Insummary, Prof. Feng-Gang Sun et al have reported a practical nickelcatalyzed C−S bond construction reaction via the cross-coupling of arylhalides with readily available ketene dithioacetals asthe thiol donors. A range of diverse aryl-alkyl thioethers areobtained in good yields under base-fr...
otheronedoestheadditionofbaseandrecordsthedata.Theserolesmaybereversedforthe studyofthesecondsolventsystemsothateachstudenthasafeelfordifferentaspectsofthe experiment.Eachstudentpairwillbeassignedoneofthealkylhalideslistedabovetostudy. Datafortheotherhalide’skineticstudymaybeobtainedfromanothergroup. ...
Light-driven C–O coupling of carboxylic acids and alkyl halides over a Ni single-atom catalyst Article 15 June 2023 Data availability The data that support the findings of this study are available within the paper and its supplementary information files. The X-ray crystallographic coordinates ...
Visible light-induced room-temperature Heck reaction of functionalized alkyl halides with vinyl arenes/heteroarenes. Angew. Chem. Int. Ed. 56, 14212–14216 (2017). Article CAS Google Scholar Wang, G.-Z., Shang, R., Cheng, W.-M. & Fu, Y. Irradiation-induced Heck reaction of ...
Alkylmercury(II) halides, RHgX, form 1 : 1 adducts in benzene solution with heterocyclic bases; the adduct stability is very low (K < 1), though more stable adducts (10 < K < 100 approximately) are formed with the bidentate bases, 1,10-phenanthroline and N,N,N′,N′-tetramethyl-1,...
beenpublished,continuingtoexplorethesubstratescopeofthisreaction.Whileinitial researchinthefieldfocusedonthecouplingofalkylgroups,mostfutureworkinvolved themuoresyntheticallyusefulcouplingofvinyl,alkenyl,aryl,and allylorganostannanestohalides.Duetotheseorganotinreagent’sstabilitytoairand ...
A novel stereoselective one-pot conversion of alcohols into alkyl halides mediated by N,N'-diisopropylcarbodiimide. Alcohols can be converted in high yields to the corresponding alkyl halides in a one-pot procedure via the corresponding O-alkylisourea; very short reactio... Stefano,Crosignani,Bri...
[When planning a Wittig, it’s generally best to use a primary alkyl halide (or alkyl sulfonate) here, as secondary alkyl halides don’t work as well. ] The C-H bond adjacent to the phosphorus is relatively acidic [Note 2] and can be deprotonated with strong base to give the ylide ...