S. UEMURA, ET AL.: " The reaction of alkyl halides with mercury(II) and potassium thioacetates and selenocyanates " BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, vol. 51, no. 6, June 1978 (1978-06), pages 1818-1820, XP002160256 Japan Publications Trading Co., Tokyo, JP ISSN: 0009-...
The reaction of the bis(1,2-dicyanoethylenedithiolato)lead(II) ion, Pb(mnt) 2− 2, with various organohalides has been examined and found to yield the halo(1,2-dicyanoethylenedithiolato)lead(II) ion Pb(mnt)X − (X = Br, I) and the 1,2-di(alkylmercapto) 1,2-dicyanoethylene...
Intermolecular Heck reaction of common alkyl halides, a longstanding problem in palladium catalysis, is realized with a simple Pd/dppf catalyst. Both primary and secondary alkyl halides are suitable for coupling with aromatic olefins. Single electron transfer from (dppf)Pd0to alkyl halide initiated the...
A cobalt complex, CoCl2[1,6-bis(diphenylphosphino)hexane], catalyzes an alkylation reaction of styrenes in the presence of Me3SiCH2MgCl in ether to yield beta-alkylstyrenes. A variety of alkyl halides including alkyl chlorides can be employed as an alkyl source. A radical mechanism is strongl...
The Friedel-Crafts alkylation synthesizes alkylated products, such as alkylbenzenes, via the reaction of alkyl halides or alkenes with aromatic hydrocarbons. The reaction removes a hydrogen atom on the aromatic ring and replaces it with an electrophile. Thus, it occurs via electrophilic aromatic s...
(A) Previous alkyl-Heck-type reactions by Oshima, Alexanian, Zhou, Li, Fu, Lei, and Nishikata. (B) Previous decarboxylative vinylic alkylation with aliphatic acid derivatives. (C) This work: Brønsted acid-catalyzed alkyl-Heck-type reaction. As is well known, alkyl halides are one of the...
5)Irradiation-Induced Heck Reaction of Unactivated Alkyl Halides at Room Temperature J. Am. Chem. Soc.2017, 139, 50, 18307–18312 评述 Heck反应自发现以来,就广泛用于烯烃衍生化,C-C键的高效构建方法,使得该反应在有机合成、药物制备、天然产物合成中得到非常广泛的应用。虽然,该反应的机理还在持续深入的...
SelectiveActivation of Alkyl Halides Toward Cross-coupling via Bimolecular HomolyticSubstitution (SH2) SelectedScopeofBromide−BromideCross-ElectrophileCoupling ScopeofAlcohol−BromideCross-ElectrophileCoupling Strongstericeffectonreactivityofprimarybromidecouplingpartners,aswellasastrongeffectfornonhalideelectrophiles:...
mustperformthekineticstudiesworkinginpairs.Onestudentwillmeasurethetimewhilethe otheronedoestheadditionofbaseandrecordsthedata.Theserolesmaybereversedforthe studyofthesecondsolventsystemsothateachstudenthasafeelfordifferentaspectsofthe experiment.Eachstudentpairwillbeassignedoneofthealkylhalideslistedabovetostudy. Data...
A novel stereoselective one-pot conversion of alcohols into alkyl halides mediated by N,N'-diisopropylcarbodiimide. Alcohols can be converted in high yields to the corresponding alkyl halides in a one-pot procedure via the corresponding O-alkylisourea; very short reactio... Stefano,Crosignani,Bri...