VEGFR-TKIs联合免疫治疗在IMDC低危人群中疗效的Meta分析 Efficacy of VEGFR-TKIs plus immune checkpoint inhibitors in metastatic renal cell carcinoma patients with favorable IMDC prognosis 背景:PD-1/PD-L1免疫抑制剂(ICI)联合抗血管内皮生长...
[9] Lee HJ, Shin DH, Kim SY, Hwang CS, Lee JH, Park WY, Choi KU, Kim JY, Lee CH, Sol MY, Rha SH, Park SW. TFE3 translocation and protein expression in renal cell carcinoma are correlated with poor prognosis. Histopathology. 2018 Nov;73(5):758-766. doi: 10.1111/his.13700. E...
Blood Type May Affect RCC Prognosis. (cover story)The article focuses on a study conducted by the researchers at the Medical University of Vienna in Austria led by Tobis Klatte, suggesting the association of the blood group O in patients having renal cell carcinoma with a lower risk of lymph...
Conclusion and future direction The treatment setting of advanced RCC has progressed in the last years with emerging ICIs accompanied by the advancement development of novel anti-angiogenic drugs and other therapeutics (Tables3and4). This progress brought about the amelioration of prognosis and improveme...
with some studies highlighting that a complete thrombus removal did not affect prognosis. Besides, elderly patients with comorbidity are usually unfit to undergo major cardiac surgery. Therefore, urologists deal with patients with ...
That’s not part of the IMDC risk factors and those patients have a particularly poor prognosis, so it’s important to consider the IMDC but, as a clinician in the room with the patient, [to also] consider these other factors.” Clear Cell RCC Therapeutic Choices Take Steps Forward During...
the patients can be more readily found, and that is the largest group in need of the medications. But the patients with nccRCC are really also terribly underserved. Back in the day, none of us had many options beyond surgery, so little distinction was made. The prognosis was grim all aro...
RCC was the cause of death in 14.9% of patients with small tumours vs 50.7% with large tumours.The best prognosis was among patients with small tumours diagnosed with CT. ConclusionAmong patients with small tumours, prognosis has improved along with better diagnostics, although some showed relapse...
Association between PD-L1 expression and the prognosis and clinicopathologic features of renal cell carcinoma: a systematic review and meta-analysis. Urol Int. 2020;104(7–8):533–41. Article CAS Google Scholar Kumar A, Chamoto K. Immune metabolism in PD-1 blockade-based cancer immunotherapy...
1:08 |Then, another study is showing the efficacy of different treatments in case of brain metastases. We see that brain metastasis is associated with a very poor prognosis and we have no clear efficacy of any treatments right now.