Furthermore, the endogenous Hey1 promoter is derepressed in CtBP-deficient cells. We propose that a corepressor complex containing CtIP/CtBP facilitates RBP-Jkappa/SHARP-mediated repression of Notch target genes. 展开 关键词: Retinol-Binding Proteins Repression novel receptor Pattern 视黄A醇结合蛋白...
AGO-RBP crosstalk on target mRNAs: Implications in miRNA-guided gene silencing and cancerArgonaute proteinCancerRBPsmRNAsmiRISCmiRNAsMicroRNAs (miRNAs) and RNA-binding proteins (RBPs) are important regulators of mRNA translation and stability in eukaryotes. While miRNAs can only bind their target ...
NF-κB2 Is a Putative Target Gene of Activated Notch-1 via RBP-Jκ NF-κB2 (p100/p52), a member of the NF-κB/Rel family of transcription factors, is involved in the regulation of a variety of genes important for immune fu... Franz,Oswald,Susanne,... - 《Mol.cell.biol》 被引量...
We previously reported that retinol binding protein 7 (RBP7) is an endothelial-specific PPARγ target and that it is required for the protective effects of PPARγ in the endothelium. Transgenic mice expressing a dominant-negative mutation in PPARγ specifically in the endothelium (E-V290M) and ...
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NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa[J]. Mol Cell Bio1,1998,18 (4): 2077-2088.Oswald F, Liptay S, Adler G, et al. NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa[J]. Mol Cell Biol 1998; 18: 2077–2088....
EBNA2 Drives formation of new chromosome binding sites and target genes for B-Cell master regulatory transcription factors RBP-jκ and EBF1. PLoS Pathog. 12, e1005339.Lu F, Chen HS, Kossenkov AV, DeWispeleare K, Won KJ, Lieberman PM. EBNA2 drives formation of new chromo- some binding...
In the present study, we show that Mad1 recruits the histone demethylase RBP2 to the Myc target telomerase reverse transcriptase (hTERT) gene promoter to repress transcription. With differentiation of leukemic HL60 cells, Madl and RBP2 were both up-regulated, interacted, and cooccupied the ...