MMP-2 is a likely effector of endometrial menstrual breakdown. It plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Kenny et al. (2008) found that expression of MMP2 was induced upon attachment of ovarian cancer (OvCa) cells to mesot...
Western blot analysis showed decreased NLRP3, ASC, caspase-1, MMP-2/9, TLR4 and Bax protein levels after HRS treatment, while Bcl-2 expression increased after HRS treatment. These data demonstrated that HRS attenuated neuroinflammation, NLRP3 inflammasome activation, neuronal injury, and ...
In the current study, an increase in COMP, MMP1, and MMP13 in the knees of rats with OA was observed, and was reversed by combining curcumin with swimming for 4 weeks. The fact that inflammation results in the activation of the MMPs such as MMP2, MMP3, MMP9, and MMP13, which ...
real-time PCR, and ELISA, respectively. The in vivo studies showed that JH treatment significantly prevented the progression and development of RA in CIA rats through anti-inflammation and suppressing bone destruction. The in vitro studies revealed that JH could effectively attenuate the destructive ph...