Nodes represent individual GO-BP terms and are colored by the NES; thickness of the edges connecting nodes relates to the proportion of genes in common between the gene sets (see ‘Gene Set Network Diagram’ in Supplementary Methods). ncRNA, noncoding RNA. Full size image...
There has been considerable interest in discovery of the genetic architecture of complex traits, particularly age-related neurodegenerative disorders. To predict disease risk and to understand its genetic basis in humans, it is necessary to study animal
Double-labeled (i.e. pseudorabies virus- and cholera toxin B-immunoreactive) neurons were only occasionally seen in the lateral spinal nucleus and were absent in the spinal gray matter, indicating that segmental interneurons do not collateralize in long ascending sensory pathways to the midbrain and...
Schematic diagram of experimental design. A:To induce spinal cord injury, a 35 g circular rod was placed on the exposed L3 spinal segment and the spinal cord compressed in the dorso-ventral direction for 15 minutes.B:Three days after injury, the animals were randomly assigned to experimental g...
All procedures from the brain dissection under the cryostat to the measurement of monoamine contents by HPLC have been performed blind of the treatment and randomly. The results for individual compounds are expressed in pg/mg of tissue. The ratios of DOPAC/DA and 5-HIAA/5-HT, considered as ...
Peripheral nerve injury denervates muscle, resulting in muscle paralysis and atrophy. This is reversible if timely muscle reinnervation occurs. With delayed reinnervation, the muscle’s reparative ability declines, and muscle-resident fibro-adipogenic pr
The dissection areas were chosen in accordance with previous researches. A large number of DA cells in dissected tissues was maintained in 1X HBSS. Using a glass micropipette, VM tissue was cut into minute slices and then implanted into lesioned striatum (0.5 mm posterior to bregma, 2.5 mm ...
Background: Cannabinoids induce biphasic effects on memory depending on stress levels. We previously demonstrated that different stress intensities, experienced soon after encoding, impaired rat short-term recognition memory in a time-of-day-dependent ma