As in other multicellular organisms, RAS proteins play a key role in the signaling pathways that regulate cell growth and differentiation in Drosophila . Although these proteins were first identified in Drosophila using cross-species hybridization, it has been the use of classical genetics which has ...
A. et al. COSMIC: somatic cancer genetics at high-resolution. Nucleic Acids Res. 45, D777–D783 (2017). CAS PubMed Google Scholar Wellcome Sanger Institute. COSMIC Release v84. Sanger.ac.uk https://cosmic-blog.sanger.ac.uk/cosmic-release-v84/ (2018). Hobbs, G. A., Der, C. J...
Rauen Pathogenetics of the RASopathies Hum. Mol. Genet., 25 (R2) (2016), pp. R123-R132 CrossrefView in ScopusGoogle Scholar To et al., 2008 M.D. To, C.E. Wong, A.N. Karnezis, R. Del Rosario, R. Di Lauro, A. Balmain Kras regulatory elements and exon 4A determine mutation ...
1995, Cancer Genetics and Cytogenetics more F. Antillón-Klüssmann, M. García-Delgado, I. Villa-Elízaga, L. Sierrasesúmaga Mutational activation of ras genes is absent in pediatric osteosarcoma Cancer Genetics and Cytogenetics, Volume 79, Issue 1, January 1995, Pages 49–53 Original Research...
In an additional effort to correlate behavior to genetics, presence of BRAFV600E mutation, BRAF VE1 immunopositivity, or high-risk mutation (TERT promoter, TP53) excludes a diagnosis of NIFTP [15]. While the diagnostic criteria for NIFTP have helped standardize the approach towards recognizing ...
关键词: CANCER genetics ONCOGENES VIRAL genetics MOLECULAR cloning DOI: 10.1038/nrc1097 被引量: 3040 年份: 2003 收藏 引用 批量引用 报错 分享 全部来源 免费下载 求助全文 全文购买 Taylor & Francis BMJ Nature Nature (全网免费下载) Springer 查看更多 相似文献 参考文献 引证文献...
- 《Somatic Cell & Molecular Genetics》 被引量: 19发表: 1991年 Modulation of the FGF14:FGF14 homodimer interaction through short peptide fragments. Fibroblast growth factor 14 (FGF14) is a member of the intracellular FGF (iFGFs) family and a functionally relevant component of the neuronal ...
Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK Simon H. Reed School of Management, Swansea University Bay Campus, Swansea, SA1 8EN, UK Paul D. Lewis Contributions GM and PDL designed the study, AB oversaw the simulations, GM wrote the manu...
The Laboratory for Physiological Chemistry and Centre for Biomedical Genetics, Stratenum, Utrecht, The NetherlandsJohn Wiley & Sons, LtdEuropean Journal of ImmunologyAmsen, D., Kruisbeek, A., Bos, J. L. & Reedquist, K. Activation of the Ras- related GTPase Rap1 by thymocyte TCR engagement ...
Healthy skin is a mosaic of wild-type and mutant clones1,2. Although injury can cooperate with mutated Ras family proteins to promote tumorigenesis3–12, the consequences in genetically mosaic skin are unknown. Here we show that after injury, wild-type c