Track 14: Viral Infectious Diseases Viral Infectious Disease happens when a life form's body is attacked by pathogenic infections, and irresistible infection particles (virions) append to and enter vulnerable cells. There are numerous sorts of infections that cause a wide assortment of viral sickness...
Finally, GPR17 has been shown to regulate the oligodendrocyte differentiation and myelination that plays a role in several neurological diseases, including schizophrenia37. Discussion In this study, we have described a gene burden analysis of a large cohort of rare disease cases and identified 69 ...
Prion diseases cause dementia, but not Alzheimer's disease. Different genes and proteins are involved in Alzheimer’s. But in all these diseases, including Alzheimer’s, the cause is proteins that don't work the way they should and damage brain cells. Alzheimer's symptoms may get worse slowly...
On the other hand, rare genetic diseases with a cellular effect can also cause a lot of perplexities and issues for children who are victims of RGD. For instance, the Niemann-Pick Disease is a typical cellular genetic disease. Niemann-Pick disease (NPD) is inherited in an autosomal recessive...
Currently, over 70% of rare diseases have a known or presumed genetic cause4. Identifying a molecular genetic diagnosis for a child with a rare disease is the first step in delivering precision medicine to improve outcomes. Advances in genomic technologies, notably exome sequencing (ES) and more...
Background and Aim In Europe, rare diseases are considered the pathologies that affect fewer than 1 in 2000 persons. More than 6000 rare diseases were identified, and almost 80% of them have a genetic cause. Many rare disorders are characterised by a broad diversity of common symptoms and ...
These diseases may seem to be rare, but there is a significant figure that highlights just how many people are living with it but that gets a little attention due to their singularity. The challenges they face are common to millions of people across the world. The challenges ...
Now, some families are forming their own biotech businesses, acting as drug developers to find treatments for ultra-rare diseases that affect 1,000 patients or fewer. But their chances are slim. Only about 12% of drugs in clinical trials are ever approved by the FDA. And few biotech firms...
Orphanet Journal of Rare Diseases volume 2, Article number: 46 (2007) Cite this article 37k Accesses 121 Citations 7 Altmetric Metrics details Abstract Sarcoidosis is a multisystemic disorder of unknown cause characterized by the formation of immune granulomas in involved organs. It is an ...
Rare diseases are usually genetic, chronic and incurable disorders with a relatively low incidence. Developments in the diagnosis and management of rare diseases have been relatively slow due to a lack of sufficient profit motivation and market to attrac