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Extensive testing is essential to break the transmission of SARS-CoV-2, which causes the ongoing COVID-19 pandemic. Here, we present a CRISPR-based diagnostic assay that is robust to viral genome mutations and temperature, produces results fast, can be applied directly on nasopharyngeal (NP) sp...
Measurements with one GFP nanobody gate per COVID-19-positive sample served as an additional negative control. As before, the normalized response was calculated as\({\rm{normalized}} \, {\rm{response}} = (|I_{\mathrm{D}} - I_0|)/I_0\)(the current change normalized to the baseline...
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Therefore, rapid, facile, cost-effective and accessible detections for large-scale screening, in-field testing and point-of-care diagnosis of the disease are of great importance and urgency for quickly controlling the highly contagious and rapid spread of COVID-19. In this work, we first review...
COVID-19 point-of-care diagnostics FRET effect SARS-CoV-2 spike protein 1. Introduction Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the most significant pandemic around the world today and brought a terrific threat to human ...
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I watched a demo, in the same conference (eek), of a chat bot that had been put in place to help gather more details about how people were coping during lockdown due to COVID 19. What was very interesting to me (other than I manage to stop myself from screaming at the screen) wa...
The need for rapid, accurate, and scalable testing systems for COVID-19 diagnosis is clear and urgent. Here, we report a rapid Scalable and Portable Testing (SPOT) system consisting of a rapid, highly sensitive, and accurate assay and a battery-powered p