Acridine Orange 吖啶橙荧光素;3;6-Bis(dimethylamino)acridine hydrochloride 3;6-双(二甲基氨基)吖啶盐盐酸;Acridine Orange hydrochloride hydrate;Acridine Orange(AO)吖啶橙;lysosomal dye 溶酶体探针;Lysotraker;Autophagy 自吞噬;3-MA 3-甲基腺嘌呤;Rapamycin 雷帕霉素;N;N;N’;N’-Tetramethyl-3;6-acridine...
Ma Qian, Zhou Yujie, Nie Xiaomin, Yu Miao, Gao Fei, Wang Zhijian, Nie Bin, Yan Zhenxian, Ge Hailong, Jia Dean, Yang Shiwei, Liu Xiaoli, Han Hongya, Hu Bin Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China ...
Steiner JP, Connolly MA, Valentine HL, Hamilton G, Dawson TM, Hester L, et al. Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressi- ve drugs FK506, rapamycin and cyclosporin A. Nature Med 1997;3:421-8.Steiner, J. P., et al. (1997). Neurotrophic actions of non...
60 (Suppl 2): A43 -- Gutdoi:10.1136/gutjnl-2011-300857a.94Holder, B.Grant, C. R.Ma, Y.Mieli-Vergani, G.Vergani, D.Longhi, M. S.Gut
Rapamycin also mediated an obvious increase in Dil-labeled ox-LDL (Dil-ox-LDL)/LC3 and Dil-ox-LDL/LAMP1 co-localization, which was inhibited by 3-methyladenine (3-MA), an autophagic inhibitor. In addition, significant co-localization of LC3 and LAMP1 occurred in cells pretreated with ...
Abbreviations: 3-MA: 3-methyladenine; ATG: autophagy related; AV: autophagic vacuoles; Dpf: days post fertilization; GJA1: gap junction protein alpha 1; GJA3: gap junction protein alpha 3; GJA8: gap junction protein alpha 8; Hpf: hours post fertilization; MAP1LC3/LC3: microtubule associated...
Monti P, Scirpoli M, Maffi P, Piemonti L, Secchi A, Bonifacio E, Roncarolo MG, Battaglia M (2008) Rapamycin monotherapy in patients with type 1 diabetes modifies CD4 + CD25 + FOXP3+ regulatory T-cells. Diabetes 57:2341–2347...
However, when the autophagy process was inhibited by 3-MA, the effects of rapamycin became apoptotic. The Phlda1 gene was found to be up-regulated in both autophagy and apoptosis and silencing this gene was found to reduce both activities, strongly suggests that Phlda1 mediates and positively...
However, when the autophagy process was inhibited by 3-MA, the effects of rapamycin became apoptotic. The Phlda1 gene was found to be up-regulated in both autophagy and apoptosis and silencing this gene was found to reduce both activities, strongly suggests that Phlda1 mediates and positively...
17-AAG and rapamycin promote the accumulation of LC3-II and the formation of LC3 positive puncta which is inhibited by 3-MA.Michael RiedelOlaf GoldbaumLisa SchwarzSebastian SchmittChristiane RichterLandsberg