The need for speed? Examples from a randomised controlled trial in the emergency settingMyocardial InfarctionRandomise Control TrialAcute Myocardial InfarctionStudy DrugUnique ChallengeWithin the NIAMI ( Nitrates in Acute Myocardial Infarction ) Trial patients present as an emergency and clinicians aim to ...
Randomised controlled trials (RCTs) answer questions about the effectiveness of different care options: 'what effect does using treatment A or treatment B have on outcomes?' RCTs are important to nursing as they are the best study design for answering the question 'should I do this or that?
During the research, one intervention participant died in a motor vehicle accident at week 19. One control group participant reportedly began a plant-based diet from week 6 and continued in the control group. Results Of the 693 total people invited by mail, 65 (9.4%) were randomised to e...
established with the intention to embed clinical trials. Trials from the GynOp and SWEDEHEART registries are prime examples of the potential of rRCTs, when using established registries for the majority, or all, key trial procedures. It is also possible for rRCTs to facilitate the development and...
In randomised trials, rather than comparing randomised groups directly some researchers carry out a significance test comparing a baseline with a final measurement separately in each group. We give several examples where this has been done. We use simula
No consensus exists regarding which are the most effective mechanisms to promote household action on climate change. We present a meta-analysis of randomised controlled trials comprising 3,092,678 observations, which estimates the effects of behavioural
The POES has sound psychometric properties [61, 62] and has been used to detect change as a primary or secondary outcome measure in previous lifestyle interventions [63,64,65,66] and IPS trials [21, 23]. The Hospital Anxiety and Depression Scale (HADS) has 14 items and assists to ...
We examine evidence from randomized control trials (RCT) on CHW interventions in IMCI in LMIC from a realist perspective with the aim to see if they can yield insight into the working of the interventions, when examined from a different perspective. Methods The realist approach involves educing ...
(although these factors are also possible behavioural mechanisms for an intervention affect, rather than necessarily a sign of bias). Techniques of partial blinding due to deception used in other trials [30,43,44] (where the control group are not aware of the existence of the intervention) are...
Trials. 2008;9:1–11. Article Google Scholar Patel V, Weiss HA, Chowdhary N, Naik S, Pednekar S, Chatterjee S, et al. Effectiveness of an intervention led by lay health counsellors for depressive and anxiety disorders in primary care in Goa, India (MANAS): a cluster randomised ...