2023年12月20日,来自荷兰瓦赫宁根大学Dolf Weijers团队在《细胞》杂志上发表了标题为“RAF-like protein kinases mediate a deeply conserved, rapid auxin response.”的研究成果,研究发现RAF样蛋白激酶介导一种高度保守的快速生长素反应。 据介绍,植物信号分子生长素触发陆地植物和藻类的快速和慢速细胞反应。核生长素...
In this study, through a screening of specific inhibitors for the blue light-dependent H-ATPase phosphorylation in guard cells, we identified a Raf-like protein kinase, BLUE LIGHT-DEPENDENT H-ATPASE PHOSPHORYLATION (BHP). Guard cells in the bhp mutant showed impairments of stomatal opening and H...
A mutagenesis screening for ABA-insensitiveP. patensmutants revealed that a mutation in a Raf-like protein kinase cause reduced ABA sensitivity and osmotic stress tolerance50. The authors named this Raf-like protein ARK (ABA and abiotic stress-responsive Raf-like kinase). ARK is a single gene f...
The phytohormone abscisic acid (ABA) plays a major role in abiotic stress responses in plants, and subclass III SNF1-related protein kinase 2 (SnRK2) kinases mediate ABA signaling. In this study, we identified Raf36, a group C Raf-like protein kinase in Arabidopsis , as a protein that int...
Mitogen-activated protein kinase (MAPK) cascades regulate a myriad of plant biological processes, including disease resistance. Plant genomes encode a large number of MAPK kinase kinases (MAPKKKs) that can be divided into two subfamilies, namely MEKK-like kinases and Raf-like kinases. Thus far,...
The role of Raf kinase inhibi- tor protein in rheumatoid fibroblast-like synovi- ocytes invasiveness and cytokine and matrix metalloproteinase expression. Inflammation 2012; 35: 474-483.Joong Kyong Ahn,Ji-Won Hwang,Eun-Kyung Bae,Jaejoon Lee,Chan Hong Jeon,Eun-Mi Koh,Hoon-Suk Cha.The Role ...
Mitogen-activated protein kinase (MAPK)ascades play importantoles in plantesponseso various environmentaltimuli, includingighaltr drought levels.rabidopsisAP3K54 with PAS (periodircadian protein,rylhydrocarboneceptor nucleartranslocator proteinndingle-minded protein) domain isnefheaf-typeAPKKKs whoseunction...
Furthermore, a 74 kD protein, corresponding to Raf-1, was also detected in CFU-Es purified from human adult sources. Together, these studies support the hypothesis that the Raf-1 protein mediates both erythropoietin-induced and IGF-induced signal transduction in human erythroid progenitor cells....
Mammalian Ste20-like Kinase (Mst2) Indirectly Supports Raf-1/ERK Pathway Activity via Maintenance of Protein Phosphatase-2A Catalytic Subunit Levels and Co... (2010) Mammalian Ste20-like kinase (Mst2) indirectly supports Raf-1/ERK pathway activity via maintenance of protein phosphatase-2A ...
Arabidopsis Raf-Like Mitogen-Activated Protein Kinase Kinase Kinase Gene Raf43 Is Required for Tolerance to Multiple Abiotic Stresses. Virk,N,Li,D,Tian,L,Huang,L,Hong,Y,Li,X,Zhang,Y,Liu,B,Zhang,H,Song,F. PLo S One . 2015Virk, N. et al. Arabidopsis Raf-like mitogen-activated protein...