combination therapyimmune modulatorsionizing irradiationradiotherapytumor-specific immunityObject. In this prospective study, the authors offered protocol-selected patients a combination of parenteral steroids, decompression surgery, and localized cooling to preserve viable spinal cord tissue and enhance functional...
Intraoperative radiation therapy— Radiation is delivered to a tumor during surgery. Radiosensitizers— These drugs increase radiation's damaging effect on cancer cells. Radioimmunotherapy— Radioactive substances are attached to antibodies, defensive chemicals made by the body's immune system. These antibo...
Radiation therapy (RT) has historically been the most common approach used to achieve local tumor control in cancer patients. However, emerging evidences over the last decades suggest an important role for RT in modulating or amplifying the antitumor immune response upon induction of cancer cell deat...
Radiation Therapy Radiation is a very common cancer treatment. About 50% of all cancer patients will receive radiation treatment, which may be delivered before, during, or after surgery and/or chemotherapy. Radiation can be delivered externally -- where X-rays, gamma rays, or other high-energy ...
Radiation therapy fights cancer in more ways than one. Not only does it force cancer cells to self-destruct, but several studies demonstrate that it also activates the immune system to attack tumor cells. This activation can be used to boost current immunotherapies, such as anti-tumor vaccines,...
A therapy for skin conditions, including psoriasis, eczema and vitiligo, that is composed of a plant-derived ultraviolet (UV)-sensitizer compound (psoralen), combined with UVA radiation (long wavelength radiation). Impetigo A common and highly contagious skin infection that mainly affects infants and...
More than a decade ago, radiation oncologists noticed a nifty phenomenon: Sometimes radiation used locally against a tumor could excite the immune system to attack cancer systemically throughout the body. It was as if the use of radiation had somehow awoken the immune system to the presence of...
The Association Between Radiation to the Immune System and Overall Survival and Disease Progression in Non-Small Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy PURPOSE/OBJECTIVE(S) :Although the effects of effective radiation dose to the immune cells (EDRIC) in advanced stage non-...
modulated fields, and/or harnessing the abscopal effect, are viable treatment strategies. How these and different types of radiation, and combined adjuvant targeted-therapy and immunotherapy influences the inflammatory and immune response needs to be further explored and integrated into clinical practice....
RT can also upregulate both PD-1 in NK cells and PD-L1 in NPC cells via the NF-κB pathway to enable tumor cells to escape the immune system. Administrating IFN-β is widely used as a maintenance therapy to upregulate membrane-bound TRAIL on NK cells and increase the release of soluble...