Small cell carcinoma of lungThe effects on lung tissue and tumor of natural human alpha interferon (IFN) and radiotherapy were investigated in a multimodality treatment program for selected patients with small cell carcinoma of the lung (SCLC). Interferon was given first as a single agent, then ...
There are two kinds of radiation side effects: early and late. Early side effects, such asnauseaandfatigue, usually don’t last long. They may start during or right after treatment and last for several weeks after it ends, but then they get better. Late side effects, such as lung orhear...
Strictly speaking radiation is not a “drug”; radiation has the ability to produce lung disease via several pathways. The cytotoxic effects of radiation are well recognized. The changes in tissue include marked nuclear atypia of the type II pneumocytes (Fig. 12.6A) and other cells, densefibrosi...
Then the word, which was not spoken directly to me but to his nurse practioner as I was making my two-week appointment in the reception area outside the examining room: “She looks classic Cushings. I’ll be interested to get those results.” Cushings. Cushings. No– that’s not me....
The effects of pentoxifylline at a dose of 400 mg, taken orally three times a day for eight weeks, have proven to improve clinical signs, symptoms, and a reduction in lung fibrosis [77]. It significantly reduces the presence of fibrosis with alpha tocopherol (vitamin E) for six months [...
Coggle JE, Lambert BE, Moore SR (1986) Radiation effects in the lung. Environ Health Perspect 70: 261–291 PubMed CAS Google Scholar Collis CH (1981) The response of the lung to ionizing radiation and cytotoxic drugs. M.D. Thesis. University of Cambridge Google Scholar Collis CH (1982...
Radiotherapy is one of the most effective approaches to achieve tumor control in cancer patients, although healthy tissue injury due to off-target radiation exposure can occur. In this study, we used a model of acute radiation injury to the lung, in the context of cancer metastasis, to underst...
(LVEF) did not decrease with treatment. At 3 months, adjacent lung showed opacities consistent with mild inflammatory changes, which had resolved by 1 year. The authors concluded that in 5 patients with refractory VT, non-invasive treatment with electrophysiology-guided cardiac radio-ablation ...
To compare the quality of CT images of the lung reconstructed using deep learning-based reconstruction (True Fidelity Image: TFI ™; GE Healthcare) to filtered back projection (FBP), and to determine the minimum tube current–time product in TFI withou
Complex cases include patients with tumors located adjacent to critical structures, those who have received radiation previously, those with underlying interstitial lung disease (ILD) that places them at higher risk of treatment-related toxicity, or those who have limited metastatic disease outside the...