Gene ID:2693GHSR UniProt:Q92847GHSR 研究领域 细胞生物学 细胞生物学 G蛋白偶联受体 (GPCRs) 发育研究 发育研究 干细胞研究 產品图片 GTX108171 IHC-P Image Immunohistochemical analysis of paraffin-embedded CL1-0 xenograft, using GHS-R1(GTX108171) antibody at 1:100 dilution. ...
胞质尾与酪氨酸激酶SRC和局灶性粘附激酶(FAK,也称为PTK2)相互作用,介导轴突的吸引。该蛋白部分定位于脂质筏,在没有配体的情况下诱导细胞凋亡。这种蛋白作为肿瘤抑制因子发挥作用,在结直肠癌和食管癌中经常发生突变或下调。 This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the ...
Here we demonstrate that regulated overexpression of an RCAN1transgene (this gene was previously called DSCR1 or Adapt78) also stimulates expression of the GSK-3β kinase, which can antagonize the action of calcineurin. We also show that GSK-3β is regulated by RCAN1 at a post-transcriptional...
G. et al. Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes. PLoS Biol 19, e3001143 (2021). Article CAS PubMed PubMed Central Google Scholar Han, Y. et al. Identification of...
3). Variability in abundance in E3 gene deletion strains was observed in experiments conducted by both labs contributing to this study. In the context of an intact NSD pathway, deleting DOA10 increased the abundance of GFP-NS as frequently and to a similar extent as deleting RKR1. However, ...
CONCLUSION This study involved the analyses of selected single nucleotide polymorphisms across the folate receptor genes and the folate carrier gene in a large population sample. It provided evidence that the rare alleles of specific single nucleotide polymorphisms within these genes appear to be ...
ObjectiveTo study the expression and locat ion of early growth response gene-1(Egr-1),transforming growth factor-β 1(T GF-β 1),fibronectin(FN) in silicot... L Chu,LI Xiang,HU Yong-Bin,... - 《Chinese Journal of Industrial Hygiene & Occupational Diseases》 被引量: 16发表: 2004年 ...
The Down syndrome critical region 1 (DSCR1) gene encodes a regulator of calcineurin 1 (RCAN1), which is overexpressed in the patients with Down syndrome. In this study, we found that the protein expression of RCAN1 was increased by the hydrogen peroxide (H2O2). The increase of RCAN1 ...
RCAN1/DSCR1/ADAPT78UbiquitinProteasomeDegradationNedd4Regulator of Calcineurin 1 (RCAN1/DSCR1/Adapt78) gene is located in the Down syndrome (DS) region of chromosome 21, and critical for the phenotype of DS and Alzheimer disease (AD). In this report, we found that expression of Nedd4-2 ...
The RCAN1 protein (previously called calcipressin 1 or MCIP1) binds to calcineurin, a serine/threonine phosphatase (PP2B), and inhibits its activity. Here we demonstrate that regulated overexpression of an RCAN1transgene (this gene was previously called DSCR1 or Adapt78) also stimulates ...