The method of the invention is applicable to the treatment of any form of inflammatory bowel disease, including but not limited to Crohn's disease (regional bowel disease); ulcerative colitis; autoimmune and immune-mediated diseases of the small and large bowel such as lymphocytic-plasmocytic ente...
Cook et al., “Immunotherapy and vaccine—The NLRP3 inflammasome, a target for therapy in diverse disease states,” Eur. J. Immunol., 40: 595-653, (2010). Doitsh et al., “Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection,” Nature, 505:509-514, doi:10.1038...
In order to determine τ such that the pruning of nodes is conditionally independent of the properties of the nodes themselves (node mean μ and node depth ν), we use bootstrapped, in-control samples from the model for training. Using these samples, we run simulations of the EWMA Surveillanc...
The ability to express proteins within the caveolin containing vesicles during formation could have potential for vaccine development, in which antigens can be delivered in a vesicle-encapsulated form to generate a specific immune response, and for the delivery of peptide and protein therapeutics in ...
Fu et al., “Induction of MHC class i-restricted CTL response by DNA immunication with ubiquitin-influenza virus nucleoprotein fusion antigens”,1998, Vaccine, vol. 16, No. 18, p. 1711-1717. Hines et al., “Prospects for human papillomavirus vaccine development emerging HPV vaccines”, 199...
Such methods are well-known in the art, and allow for the individual peptide components to be produced by chemical or recombinant means, followed by their chemoselective ligation in an appropriate configuration or conformation or order (eg. Nardin et al, Vaccine 16, 590 (1998); Nardin et al....
Avian pathogenic E. coli (APEC) can cause avian colibacillosis, an economically important disease that contributes to bird mortality and the high costs associated with prevention and treatment. Little is known about APEC in the context of Australian cond