DNA immunisation as a form of gene therapy is a relatively new approach to vaccination. In theory, and sometimes in practice, the inoculated plasmid DNA enters the cell and the encoded proteins are expressed therein. In this way, access of the antigen to the major histocompatibility complex (...
Although immunisation with ultra-low dosages of live parasite may provide some protection against subsequent infection by the same parasite, it is difficult to cultivate large numbers of live parasite for use in a vaccine. Transport of live parasites to areas requiring administration of the vaccine,...