Recent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other ...
抗体名:Anti-G-quadruplex DNA Antibody (5E11#) 浓度:1 mg/ml % 宿主:Mouse 用途:仅用于科研 应用范围:ELISA,IF,Dot 纯度:95% 产地:France 品牌:AntibodySystem 货号:RGK60303 用途:仅用于科研 亚型:IgG2a, kappa 是否单克隆:是 免疫原:NA 保质期:1 year ...
网络四元 网络释义 1. 四元 分子生物学词汇- 生物研究- 生物谷 ... quadruplex|四显性组合quadruplex DNA|四元DNA quartering|四分(法) ... www.bioon.com|基于4个网页
Quadruplex DNA found in human cellsNature Chemical Biology
抗体:G-QUADRUPLEX DNA ANTIBODY (1H6) RGK60306 更多供应商 武汉佰乐博生物技术有限公司 联系电话: 027-65279366 18108604356 产品介绍: 中文名称:抗-DNA G-quadruplex Structures Antibody (BG4) RGK60307 英文名称:G-quadruplex DNA 纯度:95% SDS-PAGE ...
DNA and G4 RNA in mammalian cells by immunofluorescent staining16,17,18. While these elegant studies are the most direct evidence of the presence of G4s in cells, they have some potential drawbacks. The fixation process can denature the cellular DNA and induce DNA degradation20,21, and the...
DNA quadruplex researchG‐quadruplex ligandsThis chapter contains sections titleddoi:10.1002/9781118092804.ch5Zhi‐Shu HuangSchool of Pharmaceutical Sciences, Sun Yat‐sen University, Guangzhou 510006, ChinaJia‐Heng TanSchool of Pharmaceutical Sciences, Sun Yat‐sen University, Guangzhou 510006, ChinaTian...
In addition to the familiar duplex DNA, certain G-rich DNA sequences can fold into a variety of four-stranded structures, which are calledG-quadruplexes. 富含鸟嘌呤碱基的 DNA序列能够通过鸟嘌呤环的互联作用形成四链螺旋结构 ,这种结构被称为 G-四链体。
Recent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other tra...
G‐quadruplex DNAbiophysical methodsgene promotersprotein‐DNA interactionsKHSRP (KH-type splicing regulatory protein) is a multifunctional nucleic acid-binding protein that regulates various cellular processes, with critical roles in controlling gene expression. G-quadruplexes (G4s) are noncanonical nucleic...