Here, we report that pyruvate metabolism and oxidative phosphorylation pathway is enriched in OA cartilage through gene set enrichment analysis (GSEA) and expression of Pyruvate Dehydrogenase Kinase 1 (PDK1), an enzyme that can phosphorylate Pyruvate Dehydrogenase (PDH), and inhibit pyruvate fluxes ...
The meaning of PYRUVATE KINASE is an enzyme that functions in glycolysis by catalyzing especially the transfer of phosphate from phosphoenolpyruvate to ADP forming pyruvate and ATP.
中文名称:丙酮酸脱氢酶激酶1抗体,Anti-Mitochondrial Pyruvate dehydrogenase kinase 1 英文名称:Anti-Mitochondrial Pyruvate dehydrogenase kinase 1 别名:mitochondrial; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1; HGNC:8809; Mitochondrial pyruvate dehydrogenase kinase isoenzyme 1; PDK1; PDK 1; PDK-1;...
抗体名:PDK1/Mitochondrial Pyruvate dehydrogenase kinase 1 浓度:1mg/ml % 靶点:详见说明书 宿主:详见说明书 用途:仅供科研使用 应用范围:WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500,
Pyruvate dehydrogenase kinase-1 (PDK1) functions as an inhibitor of pyruvate dehydrogenase (PDH), a key rate-limitingenzymefor pyruvate conversion to acetyl-coA.PDH, which diverts glucose flux from glycolysis toOXPHOS, plays a vital linking role between these twobiological processes. In a study of...
Pyruvate dehydrogenase kinase, c-KIT, cyclin-dependent kinases, Janus kinases, FLT3 kinase, AUR-2 kinase, tyrosine kinase; 1-(2-amino-4-pyridyl)-3-phenylaminotriazoles; combination therapy with antiallergens, immunomodulators, antiproliferative agents; Alzheimer's, Parkinson's, Multiple Sclerosis, ...
dehydrogenase(E3; EC1.8.1.4) transfers the hydrogens via FAD to NAD. The same gene encodes the dihydrolipoamide dehydrogenase of pyruvate dehydrogenase and the other two alpha-ketoacid dehydrogenases. The enzyme complex is inactivated by phosphorylation ([pyruvate dehydrogenase (lipoamide)] kinase; E...
细胞丙酮酸脱氢酶激酶(pyruvate dehydrogenase kinase)活性光度法定量检测试剂盒,货号:GMS50777.1 产品编号: GMS50777.1产品规格: 20次货期状况:国内现货品牌:GENMED备注:产品详细报价和货期,说明书请咨询子科生物在线客服QQ:2811391951,或拨打客服电话13924667705。代理商:深圳子科生物科技有限公司。...
Previous studies have also shown that inhibition of PDK1 activity using a small molecule inhibitor can suppress the proliferation and growth of CRC11,12. Therefore, to regulate the Warburg effect, we focus on targeting pyruvate dehydrogenase kinase (PDK) 1. Previously, our group identified several ...
植物丙酮酸脱氢酶激酶(pyruvate dehydrogenase kinase)活性光度法定量检测试剂盒,货号:GMS50777.4 产品编号:GMS50777.4 产品规格: 20次 货期状况:国内现货 品牌:GENMED 备注:产品详细报价和货期,说明书请咨询子科生物在线客服QQ:2811391951,或拨打客服电话13924667705。